阿西尤特大学儿童医院收治的肝肾综合征患儿的临床审计

S. Fahmy, A. Ahmad, E. Hashem
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摘要

肝肾综合征(HRS)被定义为晚期肝硬化患者肾功能恶化。目的:本研究旨在评估Assiut大学儿童医院儿科肝病和肾脏病科收治的HRS患儿的管理,根据已发表的国际指南,寻找缺陷、障碍或需要改进这类病例的管理。患者与方法收集2017年3月1日至2018年2月28日期间伴有肾脏表现的晚期肝病患儿的医疗记录,筛选符合本研究纳入标准的病例。根据已通过的已公布的指南设计了结构化数据收集表。将收集到的数据制成表格,进行统计分析和讨论。结果158例病例中,仅有11例符合本研究的纳入标准。他们的资料在记录入院和随访历史资料、登记临床检查资料、重要调查资料和管理方面存在严重缺陷。最后,结果数据显示,只有两例患者的急性肾损伤恢复好转;他们都有早期的急性肾损伤诊断和适当的治疗。结论本研究显示,本研究中HRS病例的管理没有遵循任何知名的已发表的此类病例管理指南。HRS患儿的管理必须遵循已公布的国际指南,以改善此类病例的管理和结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A clinical audit on the management of children with hepatorenal syndrome admitted to Assiut University Children Hospital
Introduction Hepatorenal syndrome (HRS) is defined as worsening kidney function in patients with advanced cirrhosis. Aim The study aimed to evaluate the management of children with HRS, who were admitted to the Pediatric Hepatology and Nephrology Units, Assiut University Children Hospital, according to published international guidelines, searching for defects, obstacles, or needs to improve the management of such cases. Patients and methods Medical records of children with advanced liver disease accompanied by renal manifestations during the period from the March 1, 2017 to the February 28, 2018 were collected and reviewed to choose the cases that fulfilled the inclusion criteria of the present study. A structured data collection form was designed according to the adopted published guidelines. The collected data were tabulated, statistically analyzed, and discussed. Results Out of 158 collected records, only 11 fulfilled the inclusion criteria of the present study. Their data revealed a severe defect in recording the admission and follow-up historical data, registered data about the clinical examination, important investigations, and management. Finally, the outcome data revealed that recovery with improvement of acute kidney injury had occurred in only two cases; they had early acute kidney injury diagnosis and proper management. Conclusion The study revealed that management of cases with HRS in the present study was not following any well-known published guidelines for management of such cases. Recommendations Management of children with HRS must follow the published international guidelines to improve both management and outcome of such cases.
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