可扩展和高通量的生物传感平台

José M. Leitão, J. Germano, N. Roma, R. Chaves, P. Tomás
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引用次数: 3

摘要

提出了一种新型的多通道高性能嵌入式高通量生物分析系统。尽管其他基于磁阻生物芯片的集成芯片实验室解决方案已经开发出来,但它们缺乏可扩展性和计算资源,无法应对具有1000多个传感器的新型生物芯片设计。提出了一种新的可配置采集和处理体系结构,结合专用协处理器来执行信号滤波和其他计算要求高的任务,中央处理器控制整个系统。该架构映射到Zynq SoC中,证明了其支持8倍以上传感器的能力,同时确保采样频率比以前的平台高1000多倍。此外,Zynq的重构能力提供了一种机制,以适应加工和最大化的生物灵敏度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Scalable and high throughput biosensing platform
A novel multi-channel high performance embedded system capable of high throughput biological analysis is proposed in this paper. Despite other integrated lab-on-chip solutions based on magnetoresistive biochips have already been developed, they lack the scalability and computational resources to cope with new biochip designs featuring more than 1000 sensors. A new configurable acquisition and processing architecture is proposed, combining dedicated coprocessors to perform signal filtering and other computational demanding tasks, with a central processor controlling the whole system. The mapping of the architecture into a Zynq SoC demonstrated its ability to support 8 times more sensors, while ensuring a sampling frequency 1000+ times higher than the previous platforms. Furthermore, the Zynq reconfiguration abilities provide a mechanism to adapt the processing and maximize the biological sensitivity.
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