动态条件下人体主动脉血流的流固耦合:数值方法

F. Martelli, M. Milani, L. Montorsi, G. Ligabue, P. Torricelli
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引用次数: 2

摘要

本文提出了一种实际操作条件下人体主动脉血流的数值分析方法。开发了一种特殊的程序,用于从磁共振成像中导入主动脉几何形状,以便进行基于患者的分析。主动脉流的模拟计算了由心脏脉搏和血液的非牛顿特性引起的流动的动态行为。通过流体结构分析,探讨了流动瞬态性和主动脉壁变形对压力流场和组织应力的相互影响。采用有限元方法对假定为线弹性各向同性材料的主动脉壁进行结构分析;然而,不同的区域被引入来解释从升主动脉到髂总动脉的杨氏模量变化。采用网格变形技术模拟壁面变形,采用双方程湍流模型考虑湍流效应。所提出的数值方法与磁共振成像扫描仪上的测量结果进行了验证,在心脏周期内主动脉壁最大和最小变形方面发现了很好的一致性。因此,流体结构分析可以提供一个重要的工具,从磁共振成像技术扩展对主动脉系统的认识,提高对动脉硬化及其相关现象的认识,以及它们对血流结构和组织应力的依赖。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fluid-Structure Interaction of Blood Flow in Human Aorta Under Dynamic Conditions: A Numerical Approach
The paper proposes a numerical approach for the analysis of the blood flow in human aorta under real operating conditions. An ad-hoc procedure is developed for importing the aorta geometry from magnetic resonance imaging in order to have a patient based analysis. The aortic flow is simulated accounting for the dynamic behavior of the flow resulting from the heart pulse and for the non-Newtonian properties of blood. Fluid – structure analysis is carried out to address the mutual influence of the flow transient nature and the aorta walls’ deformation on the pressure flow field and tissue’s stresses. Finite element method approach is used for the structural analysis of the aorta walls which are assumed as a linear elastic isotropic material; nevertheless, different regions are introduced to account for the Young modulus variation from the ascending aorta to the common iliac arteries. Mesh morphing techniques are adopted to simulate the wall deformation and a two equation turbulence model is adopted to include the turbulence effects. The proposed numerical approach is validated against the measurements carried out on magnetic resonance imaging scanner and a good agreement is found in terms of aorta wall maximum and minimum deformation during the cardiac cycle. Therefore, the fluid-structure analysis can provide an important tool to extend the insight of the aortic system from magnetic resonance imaging techniques and improve the understanding of arteriosclerosis and the related phenomena as well as their dependence on flow structure and tissue stresses.
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