他汀类药物,广谱药物的作用和益处

Ildefonzo Arocha-Rodulfo
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引用次数: 0

摘要

因此,血脂异常的预防和治疗应被视为个人心血管预防干预措施的一个组成部分,应主要针对高危人群,他们将受益最多。他汀类药物是治疗血脂异常最常用的药物。近几十年来,许多临床试验已经证明,这些药物通过一级和二级预防在异质人群中降低心血管死亡率和主要非致命性动脉粥样硬化血栓事件的有效性。这组药物是美国和欧洲指南推荐的一部分,应该开给所有已经有心血管事件且没有特定禁忌症的患者。然而,很大一部分本应受益于他汀类药物治疗的患者并没有接受他汀类药物治疗,而是被开了低剂量或有限时间的处方。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Estatinas, drogas de amplio espectro de acción y beneficios
Prevention and treatment of dyslipidemia should therefore be considered as an integral part of individual cardiovascular prevention interventions, which should be addressed primarily to those at higher risk who will benefit most. Statins are the most commonly used options for the pharmacologic treatment of dyslipidemia. In recent decades, numerous clinical trials have demonstrated the efficacy of these drugs to reduce cardiovascular mortality and major non-fatal atherothrombotic events in heterogeneous populations through both primary and secondary prevention. This group of drugs is part of the recommendations of both US and European guidelines, and should be prescribed to all patients who have already had a cardiovascular event and have no specific contraindication. However, a large percentage of patients that would benefit from a statin treatment do not receive them, have been prescribed a low dose or for a limited time.
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