Maintenance of Anesthesia in Paranasal Endoscopic Sinus Surgery: Sevoflurane or Isoflurane? Which One Is Better?

Background: Volatile anesthetics are the most prevalent drugs in maintenance of anesthetics and their platelet effects are compared. Functional endoscopic sinus surgery is known as a common type of nasal surgery. One of the most problems in this surgery is the blood filling up the nose or obscuring the lens of the camera as well as the surgeon’ view. It can cause the procedure take longer or accidently damage surrounding structures such as eye and brain. Objectives: This study was performed for comparing the effectiveness of isoflurane and sevoflurane on the bleeding rate of functional endoscopic sinus surgery (FESS). Methods: This study is a triple blind study on elective functional endoscopic sinus surgery. A total of 23 patients were assigned to each group, and after informed consent, isoflurane was administered for one and sevoflurane for another group. The evaluation was performed by an anesthetic assistant who arrived at the end of study plus the grade score. The surgeon also evaluated the extent of bleeding during the surgery. The results were assessed by Spearman and Mann-Whitney tests. Results: the average age of isoflurane group (43.3) was older than the sevoflurane group (33.96). Systolic blood pressure was also higher in the isoflurane group (141) than in the sevoflurane group (133.6). Conclusions: There was no difference between the bleeding rate and grade score of surgeons. There was no difference between the systolic blood pressure and the bleeding rate either.