分型乙状结肠造口术和环形乙状结肠造口术治疗肛肠畸形(ARM)的疗效比较研究

Dr. Md. Delwar Hossain, Dr. Ashrarur Rahman, Dr. Md. Saifullah, Dr. Kazi Md. Noor-ul Ferdous
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摘要

背景:肛肠畸形(ano直肠Malformation, ARM)是世界上常见的先天性畸形之一。治疗ARM有多种手术选择。结肠造口术通常作为新生儿高、中度肛肠畸形的第一阶段。本研究的目的是比较乙状结肠分离造口术和乙状结肠环造口术治疗肛肠畸形的临床效果。材料和方法:本前瞻性比较研究于2018年3月至2021年2月在孟加拉国Shishu医院和研究所儿科外科学院进行了130例7天大的肛肠畸形(ARM)患儿。在与监护人进行适当咨询后获得知情同意。随机分为乙状结肠造瘘组(组1=65例)和乙状结肠袢造瘘组(组2=65例)。两组比较参数为手术时间、术后伤口感染、皮肤擦伤、结肠造口脱垂、造口后缩回、造口旁疝等并发症。术后随访2个月。结果:1组患者平均年龄为2.43±1.39d, 2组患者平均年龄为2.61±1.73 d,其中男性居多。两组手术时间差异极显著(0.0001)。术后1组26.15%的患者出现皮肤擦伤,2组29.23%的患者出现皮肤擦伤。第1组有6.15%的患者出现伤口感染,但无一例患者出现脱垂、结肠造口后缩及造口旁疝。2组伤口感染1.54%,脱垂15.38%,结肠造口后缩6.15%,无造口旁疝发生。两组结肠造口脱垂的差异有统计学意义(p=0.042)。结论:在我们的研究中,环形结肠造口组出现不同造口相关问题的频率更高,但差异无统计学意义。在实验组中,气孔脱垂明显减少。鉴于这些结果,应建议对新生儿ARM分造口。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outcome of Divided and Loop Sigmoid Colostomy for the Management of Anorectal Malformation (ARM): A Comparative Study
Background: Anorectal Malformation (ARM) is one of the common congenital anomalies in the world. There are various surgical options for management of ARM. Colostomy is usually performed as a first stage in a new born with high and intermediate variety of anorectal malformations. The aim of the study was to compare the clinical outcomes between divided and loop sigmoid colostomy for the management of anorectal malformations. Material and Methods: This prospective comparative study was conducted on 130 pediatric patients at the Faculty of Pediatric Surgery, Bangladesh Shishu Hospital and Institute, who were admitted with anorectal malformations (ARM) up to 7 days of age, from March 2018 to February 2021. Informed consent was obtained after proper counselling with the guardian. They were randomly assigned to the divided sigmoid colostomy group (group 1=65 neonates) and loop sigmoid colostomy group (group 2=65 neonates). The comparative parameters between two groups were the operation time, post-operative complications such as wound infection, skin excoriation, prolapse of colostomy, retraction of colostomy and parastomal hernia. All patients were followed up for 2 months post-operatively. Results: The mean age of the patients was 2.43±1.39days in group 1 and in group 2, the mean age was 2.61±1.73 days where majority of the patients were male. The statistical difference between the two groups regarding operation time was highly significant (0.0001). After operation, 26.15% patients developed skin excoriation in group 1 where in group 2, 29.23% patients developed skin excoriation. In group 1, 6.15% patients developed wound infection but none of them developed prolapse, retraction of colostomy and parastomal hernia. On the other hand, in group 2, 1.54% patient developed wound infection, 15.38% patients developed prolapse and 6.15% patients developed retraction of colostomy and no patient experienced parastomal hernia. The statistical difference between the two groups regarding prolapse of colostomy was significant (p=0.042). Conclusion: In our study, the frequency of different stoma-related problems was greater in the loop colostomy group, although being statistically insignificant. In the divided group, there was significantly less stoma prolapse. In light of these results, divided stoma should be suggested for newborns with ARM.
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