坏疽性小肠梗阻的预后及相关因素评估

A. Abdulkadir, Fasil Wondmu Wale, Dumessa Edessa
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摘要

1.1. 背景:小肠阻塞占急性腹部疾病住院患者的15%,其中高达30%的患者需要手术干预。埃塞俄比亚是肠梗阻是发病率和死亡率主要原因的国家之一。1.2. 目的:评估2016年1月1日至2020年12月31日在希沃特法那专科医院外科病房住院的坏疽性小肠梗阻患者的预后和相关因素。1.3. 方法:回顾性横断面研究2016年1月1日至2020年12月31日在希诺特法那专科医院外科病房收治的所有坏疽性小肠梗阻患者。在本研究中,开发了一个定制的数据抽象表,用于从患者的医疗记录中获取数据。捕获的数据被编码,输入到EpiINFo并导出到社会科学软件的统计包,版本22.0。进行分析。为了总结本研究考虑的患者的人口学和临床特征,采用了描述性统计,如百分比和频率。在双变量分析中,所有p值< 0.3的变量都被考虑用于多变量logistic回归分析。估计比值比和95%置信区间来衡量这种关联的强度。p值小于或等于0.05时表示有统计学意义。1.4. 结果:本研究共纳入并最终分析了91例患者。在这52例(57.1%)患者中,坏疽性小肠梗阻手术效果不佳。术后并发症发生率最高的是吻合口漏(29.5%),其次为手术部位感染(25.5%)和肺炎(23.6%)。坏疽性小肠梗阻的不良手术处理结果也记录了15例术后死亡。坏疽性小肠梗阻的手术处理结果与术前病程、术后住院时间和发病时休克有显著相关。结论:在本研究中,坏疽性小肠梗阻的手术处理结果大部分患者预后不佳,但预后良好的患者比例也相当可观。因此,设计一种策略,解决与不良结果相关的因素,可能有助于进一步增加坏疽性小肠梗阻手术治疗良好结果的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of Outcome of and Factors Associated with Gangrenous Small Bowel Obstruction
1.1. Background: small bowel obstructions account for 15% of hospital admissions for acute abdominal complaints and up to 30% of these patients will require operative intervention. Ethiopia is one of the countries where intestinal obstruction is a major cause of morbidity and mortality. 1.2. Objectives: To assess outcomeand factors associated with gangrenous small bowel obstruction among patients admitted to surgical ward of Hiwot Fana Specialized University Hospital from January 1, 2016-December 31, 2020. 1.3. Methods: A retrospective cross-sectional study was conducted on all patients with gangrenous small bowel obstruction admitted to surgical ward of Hiwot Fana Specialized University Hospital from January1, 2016-December 31,2020. For this study, a customized data abstraction form was developed for data capturing from medical records of the patients. The captured data was coded, entered to EpiINFo and exported to statistical package for social sciences software, version 22.0. for analysis. To summarize demographic and clinical characteristics of the patients considered for this study, descriptive statistics such as percent and frequency was employed. All variables with P-value < 0.3, during bi-variable analyses were considered for multivariable logistic regression analyses. Odds ratio along with 95% Confidence interval were estimated to measure the strength of the association. Level of statistical significance was declared at p value less or equal to 0.05. 1.4. Results: A total of 91patiens were included and finally analyzed in this study. From these 52 (57.1%) patients have un favorable surgical outcomes of gangrenous Small bowel obstruction. Of the 52 patients with unfavorable outcome, the most common postoperative complication occurred was anastomotic leak (29.5) followed by surgical site infection (25.5%) and pneumonia (23.6%) . A total of 15 postoperative deaths were also documented as unfavorable surgical management outcomes of gangrenous Small bowel obstruction. Three factors including duration of illness before surgery, length of hospital stay after surgery and shock at presentation were significantly associated withthe surgical management outcome of gangrenous Small Bowel Obstruction. 1.5. Conclusion: In this study, the majority of patients had unfavorable surgical management outcomes of gangrenous Small Bowel Obstruction, however the proportion of patients with favorable outcomes was considerable. Thus, designing a strategy that address the factors associated with unfavorable outcomes could be helpful to further increase the likelihood of favorable surgical management outcomes of gangrenous Small Bowel Obstruction.
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