Mohammad El Shewi, Mohebat Goda, W. A. Abdel Halim, Hany R. Elkholy
{"title":"血清白细胞介素5作为慢性胃肠道上段症状患者嗜酸性食管炎的指标","authors":"Mohammad El Shewi, Mohebat Goda, W. A. Abdel Halim, Hany R. Elkholy","doi":"10.21608/aeji.2022.122661.1205","DOIUrl":null,"url":null,"abstract":"in serum by ELISA was measured in all subjects. Results: By histopathological examination, six patients (7.5%) were diagnosed to have EoE. Endoscopic esophageal furrows, fissures/wrinkles; white exudate/granularity and concentric rings (trachealization) were significantly more frequent in patients with EoE than non EoE. Median concentration of serum IL-5 in EoE patients was 222.2pg/ml with range 187.5-307pg/ml while, it was 32.1pg/ml with range 15.6-113.6pg/ml in non EoE patients and 11.8pg/ml with range 13.4-38.2pg/ml in controls with P value < 0.001. ROC curve analysis showed that serum IL-5 can significantly predict EoE at a cut-off value of ≥103.2pg/ml with sensitivity 0.989 and = 0.96-1.0. Conclusion: Serum 5 could be an for eosinophilic esophagitis in patients with upper GIT However,","PeriodicalId":261891,"journal":{"name":"Afro-Egyptian Journal of Infectious and Endemic Diseases","volume":"4 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Serum Interleukin 5 as an Indicator of Eosinophilic Esophagitis in Patients with Chronic Upper GIT Symptoms \",\"authors\":\"Mohammad El Shewi, Mohebat Goda, W. A. Abdel Halim, Hany R. Elkholy\",\"doi\":\"10.21608/aeji.2022.122661.1205\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"in serum by ELISA was measured in all subjects. Results: By histopathological examination, six patients (7.5%) were diagnosed to have EoE. Endoscopic esophageal furrows, fissures/wrinkles; white exudate/granularity and concentric rings (trachealization) were significantly more frequent in patients with EoE than non EoE. Median concentration of serum IL-5 in EoE patients was 222.2pg/ml with range 187.5-307pg/ml while, it was 32.1pg/ml with range 15.6-113.6pg/ml in non EoE patients and 11.8pg/ml with range 13.4-38.2pg/ml in controls with P value < 0.001. ROC curve analysis showed that serum IL-5 can significantly predict EoE at a cut-off value of ≥103.2pg/ml with sensitivity 0.989 and = 0.96-1.0. Conclusion: Serum 5 could be an for eosinophilic esophagitis in patients with upper GIT However,\",\"PeriodicalId\":261891,\"journal\":{\"name\":\"Afro-Egyptian Journal of Infectious and Endemic Diseases\",\"volume\":\"4 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-04-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Afro-Egyptian Journal of Infectious and Endemic Diseases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21608/aeji.2022.122661.1205\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Afro-Egyptian Journal of Infectious and Endemic Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/aeji.2022.122661.1205","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Serum Interleukin 5 as an Indicator of Eosinophilic Esophagitis in Patients with Chronic Upper GIT Symptoms
in serum by ELISA was measured in all subjects. Results: By histopathological examination, six patients (7.5%) were diagnosed to have EoE. Endoscopic esophageal furrows, fissures/wrinkles; white exudate/granularity and concentric rings (trachealization) were significantly more frequent in patients with EoE than non EoE. Median concentration of serum IL-5 in EoE patients was 222.2pg/ml with range 187.5-307pg/ml while, it was 32.1pg/ml with range 15.6-113.6pg/ml in non EoE patients and 11.8pg/ml with range 13.4-38.2pg/ml in controls with P value < 0.001. ROC curve analysis showed that serum IL-5 can significantly predict EoE at a cut-off value of ≥103.2pg/ml with sensitivity 0.989 and = 0.96-1.0. Conclusion: Serum 5 could be an for eosinophilic esophagitis in patients with upper GIT However,
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