泡腾片的概念、制备及表征综述

Prajapati Bg, Mishra O
{"title":"泡腾片的概念、制备及表征综述","authors":"Prajapati Bg, Mishra O","doi":"10.51737/2766-5232.2021.010","DOIUrl":null,"url":null,"abstract":"Effervescent tablets are easy to consume due to this they are getting popular over other oral dosage forms. Effervescent tablets get break when they are put in water or juice which causes tablet to dissolve and form a solution. USFDA redefined the definition to Effervescent tablet is a tablet intended to be dissolved or dispersed in water before administration. Effervescent tablets consists of acids/acid salt, carbonates and hydrogen carbonates, flavour, sweetener, etc. which release carbon dioxide when it is added to water. Following chemical reaction takes place in effervescent tablets [1]. C6H8O7 (aq) + 3NaHCO3 (aq) → Na3C6H5O7 (aq) + 4H2O + 3CO2 (g) ↑ Citric acid + Sodium bicarbonate → Sodium citrate + Water + Carbon dioxide The above reaction occurs due to presence of water, because water is one of the reaction product which accelerates the reaction, leading to difficulty in stopping the reaction. Due to this reason manufacturing and storage of effervescent product is planned by minimizing their contact with water [2,3].","PeriodicalId":131899,"journal":{"name":"SunText Review of Pharmaceutical Sciences","volume":"31 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Concept, Manufacturing and Characterization of Effervescent Tablets: A Review\",\"authors\":\"Prajapati Bg, Mishra O\",\"doi\":\"10.51737/2766-5232.2021.010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Effervescent tablets are easy to consume due to this they are getting popular over other oral dosage forms. Effervescent tablets get break when they are put in water or juice which causes tablet to dissolve and form a solution. USFDA redefined the definition to Effervescent tablet is a tablet intended to be dissolved or dispersed in water before administration. Effervescent tablets consists of acids/acid salt, carbonates and hydrogen carbonates, flavour, sweetener, etc. which release carbon dioxide when it is added to water. Following chemical reaction takes place in effervescent tablets [1]. C6H8O7 (aq) + 3NaHCO3 (aq) → Na3C6H5O7 (aq) + 4H2O + 3CO2 (g) ↑ Citric acid + Sodium bicarbonate → Sodium citrate + Water + Carbon dioxide The above reaction occurs due to presence of water, because water is one of the reaction product which accelerates the reaction, leading to difficulty in stopping the reaction. Due to this reason manufacturing and storage of effervescent product is planned by minimizing their contact with water [2,3].\",\"PeriodicalId\":131899,\"journal\":{\"name\":\"SunText Review of Pharmaceutical Sciences\",\"volume\":\"31 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"SunText Review of Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.51737/2766-5232.2021.010\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"SunText Review of Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51737/2766-5232.2021.010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3

摘要

泡腾片很容易食用,因此它们比其他口服剂型更受欢迎。泡腾片放在水或果汁中会破裂,导致片剂溶解并形成溶液。美国食品药品监督管理局重新定义泡腾片是指在给药前溶解或分散在水中的片剂。泡腾片由酸/酸盐、碳酸盐和碳酸盐、香精、甜味剂等组成,当加入水中时会释放出二氧化碳。泡腾片[1]中发生如下化学反应。C6H8O7 (aq) + 3NaHCO3 (aq)→Na3C6H5O7 (aq) + 4H2O + 3CO2 (g)↑柠檬酸+碳酸氢钠→柠檬酸钠+水+二氧化碳上述反应是由于水的存在而发生的,因为水是加速反应的反应产物之一,导致反应难以停止。由于这个原因,泡腾品的制造和储存是通过尽量减少它们与水的接触来规划的[2,3]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Concept, Manufacturing and Characterization of Effervescent Tablets: A Review
Effervescent tablets are easy to consume due to this they are getting popular over other oral dosage forms. Effervescent tablets get break when they are put in water or juice which causes tablet to dissolve and form a solution. USFDA redefined the definition to Effervescent tablet is a tablet intended to be dissolved or dispersed in water before administration. Effervescent tablets consists of acids/acid salt, carbonates and hydrogen carbonates, flavour, sweetener, etc. which release carbon dioxide when it is added to water. Following chemical reaction takes place in effervescent tablets [1]. C6H8O7 (aq) + 3NaHCO3 (aq) → Na3C6H5O7 (aq) + 4H2O + 3CO2 (g) ↑ Citric acid + Sodium bicarbonate → Sodium citrate + Water + Carbon dioxide The above reaction occurs due to presence of water, because water is one of the reaction product which accelerates the reaction, leading to difficulty in stopping the reaction. Due to this reason manufacturing and storage of effervescent product is planned by minimizing their contact with water [2,3].
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信