用于液体提取和药物输送的微针阵列

Ran Liu, Xiaohao Wang, Zhaoying Zhou, J.D. Williams
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引用次数: 2

摘要

微机电系统(MEMS)是一个快速增长的领域的兴趣广泛的应用。微加工技术在生物医学领域的应用是一个快速发展的领域。生物医学工业感兴趣的一个应用是微针的开发。MEMS技术为生物医学领域带来了新的手段。本文介绍了用于液体提取或药物输送的微针阵列的设计和制造。中空的SU-8微针阵列是通过UV-LIGA技术在玻璃基板上制造的。所制空心微针的长度为300 /spl μ m,直径为80 /spl μ m。微针为生物医学分析提供了一种高效、安全、无痛的新方法。微针阵列可以与无板流体泵一起构建,在化学和生物医学领域具有潜在的应用,用于局部化学分析,可编程药物输送系统以及非常小的精确流体采样。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microneedles array for fluid extraction and drug delivery
Micro electro-mechanical systems (MEMS) are rapidly growing area of interest for a broad spectrum of applications. One particularly fast-growing area is biomedical applications for micromachining technologies. One application of interest to the biomedical industry is the development of microneedles. MEMS technology brings new means for biomedical field. The design and fabrication of the microneedle array for fluid extraction or drug delivery are presented in this paper. The hollow SU-8 microneedle array is fabricated on a glass substrate, by UV-LIGA techniques. The fabricated hollow microneedles is 300 /spl mu/m in length and 80 /spl mu/m in diameter. The microneedle provide novel biomedical analyzing method with efficiency, safety and no pain to the human skin. The microneedle array, which may be built with no-board fluid pumps, have potential applications in the chemical and biomedical fields for localized chemical analysis, programmable drug-delivery systems, and very small, precise fluids sampling.
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