卵巢交界性肿瘤25例回顾性分析

Ş. Baran, B. Pinar, Cilesiz Goksedef, H. Görgen, A. Çetin
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引用次数: 1

摘要

目的:根据临床特征、治疗方法、复发率和生存率来判断卵巢交界性肿瘤。材料与方法:本研究纳入25例病例。从医院记录中揭示了人口统计学和临床结果、手术方法、疾病分期、复发和存活情况。数据采用SPSS 13.0统计软件进行分析。结果:平均年龄42.7±17.9岁。大多数患者处于绝经前(n=19, 76%)。肿瘤平均大小为13.44±9.37 cm(范围4 ~ 30 cm),浆液型16例,粘液型9例。浆液性和黏液性肿瘤的平均肿瘤大小分别为9.44±6.78 cm、20.56±9.4 cm,差异有统计学意义(p=0.007)。17例(68%)患者术前肿瘤标志物升高。冷冻切片22例(88%),冷冻切片准确率90%。在手术过程中。大多数患者采用全腹子宫切除双侧输卵管卵巢切除术(TAH-BSO) (n=12), 6例患者采用膀胱切除术,其余患者采用单侧卵巢切除术(USO) (n=7)。大多数病例为I期(n=23, 92%)。复发4例(16%),其中2例行膀胱切除术,其余行USO治疗。TAH-BSO组无复发。结论:交界性肿瘤预后良好,多发生在绝经前。建议的治疗方法是用TAH-BSO进行手术分期。有生育欲望的年轻患者可选择膀胱切除术,但患者应注意高复发率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
RETROPECTIVE ANALYSIS OF 25 CASES WITH BORDERLINE OVARIAN TUMORS
SUMMARY Objective: To determine the borderline ovarian tumors according to clinical features, treatment methods, recurrence and survival rates. Material and methods: Twenty-five cases were included to this study. Demographic and clinical findings, surgical methods, stage of disease, recurrences and survivals were revealed from hospital records. Data were analyzed with SPSS 13.0. Results: Mean age were 42.7±17.9. Most of the patients were in premenopausal (n=19, 76%). Mean tumor size were 13.44±9.37 cm (range 4-30 cm) and 16 of the patients had serous and 9 of them had musinous histologic type. Mean tumor size of serous and mucinous tumors were 9.44±6.78 cm, 20.56±9.4 cm, respectively and the difference was statisticallly significant (p=0.007). Tumor markers were elevated in 17 of the patients (68%) before the surgery. Twenty-two patients had frozen section (88%), accuracy rate of the frozen section was 90%. during surgery. Most of the patients were treated with total abdominal hysterectomy bilateral salpingo-oophorectomy (TAH-BSO) (n=12), 6 of the patients were treated with cystectomy and the others were treated with unilateral oophorectomy (USO) (n=7). Most of the cases were stage I (n=23, 92%). Recurrence of the disease was detected in 4 patients (16%) and 2 of them were treated with cystectomy and the others were treated with USO. No recurrence was detected in TAH-BSO group. Conclusions: Borderline tumors have perfect prognosis and most of the cases are premenopausal. The suggested treatment is surgical staging with TAH-BSO. Cystectomy might be chosen in young patients with fertilty desire, however, patients should be warned for high recurrence rates.
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