Interleukin-4, Interleukin-1beta, and Creatine Kinase Changes to the DeLorme and Oxford Resistance Training Techniques

Background: Exercise intensity sequence of resistance training (RT) has a key role in the physiological response and adaptations. Objectives: The aim of the present study was to compare the effect of DeLorme and Oxford resistance training techniques on the concentration of interleukin-4 (IL-4), interleukin-1 beta (IL-1beta) and creatine kinase (CK) enzyme in overweight men. Methods: Thirty overweight young men (25 ≤ BMI < 30) voluntarily participated in the present study and were randomly assigned to the DeLorme (Del; n = 10), Oxford (OXF; n = 10) resistance training techniques and control (Con; n = 10). Del performed 4-5 sets at intensity of 50% of one-maximum repetition (1RM) for warm up, the second set with 85% of 1RM, the third set at 90% of 1 RM, and the fourth set at 95 of 1RM, and finally the fifth set at 100 1RM of exercise, while the OXF performed mentioned protocol exactly reverse order for eight weeks. RT was done three day/week in nonconsecutive for eight week. Blood sampling was gathered before RT, and repeated 72 hour after the last session of RT, and the levels of CK activity as well as the concentration of IL-4 and IL-1beta concentration were measured in the plasma. Results: The results showed that there was no significant difference between the Del and OXF in biochemical variables (P > 0.05). Also, in the IL-4, IL-1beta and CK, there were no improvement was found in the Del and OXF compared to the control (P > 0.05). Conclusions: Finally, it can be said that none of the Delorme and Oxford resistance training technique are preferred in improving systemic inflammatory factors, and the sequence of resistance training intensity is more or less and vice versa has no effect on improving systemic inflammatory factors.