抗氧化剂在预防老年性黄斑变性中的作用

S. Deshpande
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引用次数: 4

摘要

年龄相关性黄斑变性(ARMD)是老年人严重的、不可逆转的视力丧失的最常见原因。据估计,全世界有2000万至2500万人患有ARMD,其中800万人失明。治疗选择很少,而且通常不能成功地恢复视力。抗氧化剂能防止自由基对黄斑的损伤,有利于延缓ARMD的发展。它们还能预防ARMD的发作。抗氧化补充剂被认为可以预防ARMD的发生并延缓其发展。与年龄有关的眼病研究发现,每天补充维生素C 500毫克,维生素E 400国际单位,β -胡萝卜素15毫克,锌80毫克,铜2毫克,持续5年,可显著延缓ARMD的进展。基于这项高质量的双盲研究的结果,美国眼科学会建议中度和重度ARMD患者考虑每天服用抗氧化剂和锌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of anti-oxidants in prevention of age-related macular degeneration
Age-related macular degeneration (ARMD) is the most common cause of severe, irreversible, vision loss in elderly people. It is estimated that 20 to 25 million people suffer from ARMD worldwide, of which 8 million people experience blindness. The treatment options are few and usually not successful in restoring the vision back. The anti-oxidants prevent the damage to the macula by free radicals and are beneficial in retarding the progress of ARMD. They also prevent the onset of ARMD. Anti-oxidant supplements are indicated to prevent the onset and retard the progression of ARMD. The Age-Related Eye Disease Study found that the daily supplementation of vitamin C 500 mg, vitamin E 400 IU and beta carotene 15 mg, zinc 80 mg and copper 2 mg for five years significantly retarded the progression of ARMD. Based on the results of this high quality, double blinded study, the American Academy of Ophthalmology recommends that patients with intermediate and severe ARMD consider taking antioxidants plus zinc on a daily basis.
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