多像素光子计数器在束流PET碳治疗中的辐射损伤

F. Nishikido, Y. Hirano, A. Mohammadi, T. Yamaya
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引用次数: 0

摘要

我们正在开发用于碳离子治疗的束内成像的OpenPET。我们已经成功地展示了一个概念验证,通过开发小型OpenPET原型,我们在HIMAC中使用。实现OpenPET的主要问题之一是探测器的辐射损伤,因为许多碎片粒子会入射到目标下游的探测器上。虽然我们目前在OpenPET中使用光倍增器管,但一些小组报告了在强子治疗中使用半导体光探测器的可行性。因此,在本文中,我们测试了多像素光子计数器(MPPC)的辐射硬度,以证明其在OpenPET中用于碳离子治疗的可行性。我们使用单像素MPPC (S10931-050)来评估辐射硬度。实验是在PH2过程中进行的。12C束流能量为290MeV/u,束流强度为1.6 × 109粒子/秒(pps),是临床典型束流强度的10倍。碳离子进入并停留在水模(10 × 10 × 20 mm3)中。MPPC以30度角距水影后端30厘米。测量了22Na点源辐照10、20、30、40、50、70 min前后的能谱和暗计数谱。结果表明,随着辐照时间的增加,脉冲高度和能谱的能量分辨率有所降低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Radiation damage of the multi-pixel photon counter to be used for in-beam PET in carbon therapy
We are developing the OpenPET for in-beam imaging in carbon ion therapy. We have succeeded in showing a proof-of-concept by developing small OpenPET prototypes that we used in the HIMAC. One of the major issues to realize the OpenPET is radiation damage to detectors because a number of fragmented particles are incident on the detectors located downstream from the target. While we are currently using photo-multiplier tubes in the OpenPET, some groups reported feasibility of use of a semiconductor photo-detector in hadron therapy. In this paper, therefore, we tested radiation hardness of the multi-pixel photon counter (MPPC) to show feasibility of its use in the OpenPET for carbon ion therapy. We used a single pixel MPPC (S10931-050) to evaluate radiation hardness. The experiment was performed in the PH2 course of the HIMAC. The energy of the 12C beam was 290MeV/u and beam intensity was 1.6 × 109 particles per second (pps) which was ten times higher than the typical clinical beam intensity. The carbon ions entered and stopped in a water phantom (10 × 10 × 20 mm3). The MPPC was 30 cm from the back end of the water phantom at an angle of 30 degrees. We measured the energy spectrum for 22Na point source and the dark count spectrum before and after 10, 20, 30, 40, 50, 70 min irradiations. We found pulse height and energy resolution of the energy spectra were degraded as the irradiation time was increased.
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