S. Chapman, Grace V. Robinson, R. Shrimanker, C. Turnbull, J. Wrightson
{"title":"结节病","authors":"S. Chapman, Grace V. Robinson, R. Shrimanker, C. Turnbull, J. Wrightson","doi":"10.1093/med/9780198837114.003.0046","DOIUrl":null,"url":null,"abstract":"A multi-system disorder of unknown cause, likely resulting from the interplay of environmental and genetic factors, characterized by non-caseating granulomata and CD4+ Th1-biased T cell response in affected organs. Commonly involves the respiratory system but can affect nearly all organs. Fifty to sixty per cent of people have spontaneous remissions; others may develop chronic, and sometimes progressive, disease.","PeriodicalId":447884,"journal":{"name":"Oxford Handbook of Respiratory Medicine","volume":"19 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sarcoidosis\",\"authors\":\"S. Chapman, Grace V. Robinson, R. Shrimanker, C. Turnbull, J. Wrightson\",\"doi\":\"10.1093/med/9780198837114.003.0046\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A multi-system disorder of unknown cause, likely resulting from the interplay of environmental and genetic factors, characterized by non-caseating granulomata and CD4+ Th1-biased T cell response in affected organs. Commonly involves the respiratory system but can affect nearly all organs. Fifty to sixty per cent of people have spontaneous remissions; others may develop chronic, and sometimes progressive, disease.\",\"PeriodicalId\":447884,\"journal\":{\"name\":\"Oxford Handbook of Respiratory Medicine\",\"volume\":\"19 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oxford Handbook of Respiratory Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/med/9780198837114.003.0046\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Handbook of Respiratory Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/med/9780198837114.003.0046","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A multi-system disorder of unknown cause, likely resulting from the interplay of environmental and genetic factors, characterized by non-caseating granulomata and CD4+ Th1-biased T cell response in affected organs. Commonly involves the respiratory system but can affect nearly all organs. Fifty to sixty per cent of people have spontaneous remissions; others may develop chronic, and sometimes progressive, disease.
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