{"title":"用布尔方法解读癌症生物学","authors":"Subarna Sinha, D. Dill","doi":"10.1109/HLDVT.2016.7748269","DOIUrl":null,"url":null,"abstract":"Boolean implications (if-then rules) provide a conceptually simple, uniform and highly scalable way to find associations between pairs of random variables. In this paper, we describe how Boolean implications can be derived from large, heterogeneous cancer data sets. We demonstrate two applications of Boolean implications to discover new actionable insights in cancer biology.","PeriodicalId":166427,"journal":{"name":"2016 IEEE International High Level Design Validation and Test Workshop (HLDVT)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Deciphering cancer biology using boolean methods\",\"authors\":\"Subarna Sinha, D. Dill\",\"doi\":\"10.1109/HLDVT.2016.7748269\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Boolean implications (if-then rules) provide a conceptually simple, uniform and highly scalable way to find associations between pairs of random variables. In this paper, we describe how Boolean implications can be derived from large, heterogeneous cancer data sets. We demonstrate two applications of Boolean implications to discover new actionable insights in cancer biology.\",\"PeriodicalId\":166427,\"journal\":{\"name\":\"2016 IEEE International High Level Design Validation and Test Workshop (HLDVT)\",\"volume\":\"2 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2016 IEEE International High Level Design Validation and Test Workshop (HLDVT)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/HLDVT.2016.7748269\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2016 IEEE International High Level Design Validation and Test Workshop (HLDVT)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/HLDVT.2016.7748269","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Boolean implications (if-then rules) provide a conceptually simple, uniform and highly scalable way to find associations between pairs of random variables. In this paper, we describe how Boolean implications can be derived from large, heterogeneous cancer data sets. We demonstrate two applications of Boolean implications to discover new actionable insights in cancer biology.