模拟肾小球电屏蔽失效的动力学

H. Nieto-Chaupis
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引用次数: 1

摘要

人体的肾脏可能会受到严重的威胁,在这种情况下,电荷束的存在可能会取消它的电屏蔽,这种屏蔽起着保护作用,防止巨大的蛋白质通过尿液。本文用简单的物理方程,求出了施加在肾小球膜基底和足细胞上的负电荷分布上的电场。电力可能被视为生物纳米物联网框架内的输入信号。在本文中,我们注意到肾小球,它被认为是非常敏感的电场的存在,因为糖的偶极矩是血浆的带电成分之一。我们提供了一个简单的例子来解释诊断为2型糖尿病的患者肾脏的持续退化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Modeling the dynamics of failure of the electric shield at the renal glomerulus
The human kidney can be seriously threated in the cases where the presence of bunches of electric charges may cancel its electric shield that plays the protectionist role against the pass of giant proteins through the urine. In this paper we use simple physics equations in order to extract the electric field which exerts force on the negative charge distribution located along the glomerular membrane basement and podocytes. The electric forces might be perceived as input signals inside the framework of the Internet of the Bio-Nano Things. In this paper, we have paid attention to the renal glomerulus which is supposed to be very sensitive to the presence of electric fields because the dipole moment of sugar which is one of the charged electrically components of the blood plasm. We provided a simple example which might explain the continuous degradation of kidney in patients with diagnosis of type-2 diabetes.
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