3D打印,纳米技术和器官打印:伦理和预期的伦理分析

Richardf . Wilson
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引用次数: 0

摘要

“加强对基础生物科学的理解,主要是生物细胞之间的相互作用和相互作用,以及体内环境或自然三维微环境中的综合生物化学和结构线索,需要对工程设计和制造进行仔细定义,以应对日益复杂的生物问题所带来的挑战。[1]器官打印和组织工程可以与增材计算机辅助制造工艺技术的应用相结合,通过生物分子和生物聚合物材料的集成,创建复杂的3D生物结构的分层模式配置。器官打印这个术语被更狭义地定义为快速成型技术或计算机辅助机器人的生物医学变体,使用自组装组织球体作为构建块,逐层生物制造3D人体组织和器官。3D打印、纳米技术和器官打印的结合可以对医学实践产生巨大的影响。3D打印器官基于他的生物学原理,其中自组装过程,是指一系列过程,研究人员积极参与将原子和分子结合在分子和组件的聚集体中,最终在没有人为干预的情况下将自己排列成有序的功能实体。该分析将回顾当前的发展,并试图确定器官打印技术的未来发展,包括基于微挤压的打印、喷墨基打印和基于激光的打印,这些都是通过纳米技术和3D打印的发展来打印器官的可能方式。为了实现这一目标,需要克服许多挑战。本分析将从研究人员、医生、患者和未来患者(社会成员)的角度,集中讨论与3D器官打印相关的伦理问题,并结合纳米技术的发展。此外,将根据对3D技术、纳米技术和器官打印融合的未来可能性的预测,进行前瞻性伦理分析。一般来说,实践伦理学家试图识别和解决我们周围世界出现的社会和伦理问题。当实际伦理学家试图确定未来可能发展的伦理问题时,这些问题通常是根据这些一般伦理原则确定的。在信息技术伦理领域,预见性伦理已经出现并开始受到关注。预期伦理学的特点是关注由于新兴技术而可能出现的可预期问题。在本分析中,预期伦理学将被用于分析与3D技术、纳米技术和器官打印融合相关的未来可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
3D printing, nanotechnology and organ printing: An ethical and anticipatory ethical analysis
“An enhanced understanding of fundamental biological sciences primarily the interaction and interplay between biological cells and integrative biological chemical and structural cues within and in Vivo milieu or natural 3 dimensional micro environment requires a carefully defined role for engineering design and Manufacturing to meet the challenges presented by increasingly complex biological problems.” [1]Organ printing and tissue engineering can be used in conjunction with the application of additive computer-aided manufacturing process technologies, which create a layered pattern disposition of complex 3D bearing biological structures with biomolecular and biopolymer material integration. The term organ printing has been more narrowly defined as a biomedical variant of rapid prototyping technology or computer-aided robotic layer-by-layer at biofabrication of 3D human tissues and organs using self-assembling tissue spheroids as building blocks. The combination of 3D printing, nanotechnology, and organ printing can make a tremendous impact on the practice of medicine. 3D printed organs based upon his biological principles in which the self-assembly process, refers to a series of processes, where researchers are actively involved in combining atoms and molecules in aggregates of molecules and components, which eventually arrange themselves into ordered function entities without human intervention. The analysis will review current developments and attempt to identify future developments in organ printing techniques including, micro extrusion based printing, inkjet base printing, and laser-based printing as the possible ways that organs can be printed through developments in nanotechnology and 3D printing. In order for this to occur many challenges will need to be overcome. This analysis will focus on the ethical issues related to 3D organ printing in conjunction with developments in nanotechnology from the perspectives of researchers and physicians, patients and future patients (members of society). In addition an anticipatory ethical analysis will be conducted based upon a projection of future possibilities related to the confluence of 3D technology, nanotechnology and organ printing. In general practical ethicists attempt to identify and address social and ethical issues that arise in the world around us. When practical ethicists attempt to identify ethical problems that may develop in the future, these problems are often identified based upon these general ethical principles. Anticipatory ethics has emerged and begun to gain attention in the area of information technology ethics. Anticipatory ethics can be characterized as focusing on the problems that can be anticipated as potentially arising because of emerging technologies. In this analysis anticipatory ethics will be employed to analyze future possibilities related to the confluence of 3D technology, nanotechnology and organ printing.
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