印度西孟加拉邦三级卫生保健中心老年高血压患者左心室肥厚的患病率和决定因素

Poonam Kushwaha, Bijay Prakash Yadav
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引用次数: 1

摘要

高血压(HTN)是老年人心血管疾病中最普遍、可改变和可治疗的原因之一。慢性高血压对心血管系统的损害可导致包括左心室肥厚(LVH)在内的高血压性心脏病。这是对慢性血压(BP)的生理适应,预示预后严重,应及早诊断。因此,本研究旨在评估老年高血压患者LVH和其他心血管(CV)变化,确定心电图(ECG)与x线/胸片(CXR)证据的相关性,并找出其决定因素。研究对象为100名老年高血压患者。通过胸片和心电图评估心血管变化和LVH。还进行了其他生化研究。胸片及心电图检出LVH者分别为29%及32%。女性、年龄增长、家族史和HTN持续时间、吸烟、饮酒是LVH的独立决定因素。LVH组的平均血压、平均脉压和尿素氮均高于无LVH组。经CXR检测,LVH患者微量蛋白尿发生率明显高于LVH患者。空腹血糖和血脂异常与LVH发生的几率增加有关。在缺乏标准诊断测试的低资源环境中,胸片和心电图是检测慢性高血压患者心血管变化/ LVH的有用工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and determinants of left ventricular hypertrophy among elderly hypertensive patients attending tertiary health care center in West Bengal, India
: Hypertension (HTN) is one of the most prevalent, modifiable and treatable causes of cardiovascular diseases in the elderly. Damage to cardiovascular system due to chronic hypertension causes hypertensive heart disease including left ventricular hypertrophy (LVH). It is a physiological adaptation to chronic blood pressure (BP) indicating grave prognosis and should be diagnosed early. Present study therefore aimed to assess LVH and other Cardio-vascular (CV) changes and to ascertain correlation between the electrocardiographic (ECG) and radiographic / chest x-ray (CXR) evidences and find out their determinants among elderly hypertensive patients. 100 elderly hypertensive subjects were included in study. Cardio-vascular changes and LVH was assessed by using chest x-ray and ECG. Other bio-chemical investigations were done also.: 29% and 32% subjects had LVH detected by Chest x-ray and ECG respectively. Female, increasing age, family history and duration of HTN, smoking, alcohol consumption were found independent determinants of LVH. Subjects with LVH had higher mean blood pressures, mean pulse pressure and higher blood urea nitrogen than those without LVH. Micro-albuminuria was significantly more frequent in patients with LVH as detected by CXR. Fasting Blood sugar and dyslipidaemia was associated with greater odds of developing LVH. In low resource settings, where standard diagnostic tests are unavailable- chest x-ray and ECG are the useful tools for detection of cardio vascular changes / LVH among chronic hypertensive.
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