操纵生物应用的通用旋转机制

T. Ishikawa, H. Eda, Y. Yamamoto, K. Kawakami, L. Zhou, J. Shimizu
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引用次数: 1

摘要

近年来,在生物和微纳米技术的潜在应用中,在微米或纳米尺度的生物细胞操作和微加工等领域的需求越来越大。然而,进行直接的微观操作是非常困难的。与允许双手自由操作物体的微观工序和允许双手自由操作物体的微观工序相反,微观工序涉及在扫描电子显微镜下在很小的区域内观察和操作物体。我们目前正在开发一个生物组织和细胞工程操作系统。对于此类应用,我们需要确定物体上是否存在各种真菌、杆菌等,并从任何方向接近物体的任何一点。为了实现预期的操作,我们开发了一种双臂微型机械臂的原型,安装在一个旋转台上,围绕物体上的任何给定点,允许从任何方向接近生物物体。该操作系统还包括安装在转台上的双臂机械手和试样台。每个手臂都有三个执行器,一个叠加在另一个的顶部,以便沿着XYZ轴向移动。机械手由带放大元件的压电陶瓷作动器驱动,X、Y、z各轴可覆盖200 /spl mu/m的包膜。转台由一对垂直设置的滚轮支撑,由直流电机驱动。通过PZT致动器和平行板放大镜,滚筒副的姿态在三度内可调。在本文中,我们研究了一种允许围绕我们的微操作系统的运动原理进行控制旋转的机制的必要性,以及该系统的基本实验结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Manipulation of the universal rotational mechanism for biological application
Recently, in the potential application of biological and micro-nano technology, there are increasing demands in areas such as bio-cell manipulation and micro fabrication at the micron or nano scale. However, it is very difficult to carry out direct micro manipulations. In contrast to microscopic working procedures, which permit free manipulation of objects with the both hands, microscopic working procedures that permit free manipulation of objects with the both hands, microscopic working procedures involve the observation and manipulation of the object within a very small area under a scanning electron microscope. We are currently developing a manipulation system of biological tissue and cell engineering. For such applications, we need to ascertain the presence of various fungi, bacilli, etc. on an object and approach any point of the object from any direction. To achieve the desired operation, we have developed a proto-type of a two-arm micromanipulator mounted on a rotary table around any given point on an object, allowing biological objects to be approached from any direction. The manipulation system is further comprised of a twin-arm manipulator mounted on a rotary table and a specimen stage. Each arm comes with three actuators superimposed one on the top of the other in order to move along the XYZ axial direction. The manipulator is driven by PZT actuators with magnifier elements and able to cover an envelop as wide as 200 /spl mu/m for each axis of X, Y and Z. The rotary table is supported by a pair of rollers set perpendicularly and driven by DC motor. The attitude of the roller pair is adjustable within three-degrees by the PZT actuators together with parallel plate magnifiers. In this paper, we investigate the need for a mechanism that permits controlled rotation around the principles of motion of our micromanipulation system, and the results of basic experiments with the system.
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