COVID-19感染患者的临床特征、严重程度和结局:一项随访研究

Deldar Morad Abdulah, H. Saber
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摘要

很少有流行病学调查探讨伊拉克库尔德斯坦地区COVID-19患者的疾病结局。本研究探讨了COVID-19患者的临床和流行病学特征与预后的关系。在2020年8月15日至10月20日期间,对从私人诊所诊断出COVID-19的患者进行了随访,直到康复或死亡。新冠肺炎患者平均年龄47.12岁(6 ~ 90岁)。疲劳(76.15%)、肌痛(66.53%)、发热(65.33%)、咳嗽(62.53%)、出汗(58.52%)、头痛(56.11%)是最常见的症状。以轻度为主(350例,70.14%),其次为中度(74例,14.83%)、重度(46例,9.22%)、危重(29例,5.81%)。病死率(CFR)为5.41% (n=27),随病情加重而显著增高;轻度(0.0%)、中度(1.35%)、重度(10.87%)、危重(72.41%);P < 0.001)。危重型患者明显高龄化;中位数:中度和轻度患者的67年vs 55年;中位数:51岁vs 45岁;P < 0.001。与康复的患者相比,死亡的患者明显更老;中位数:65 vs 46岁;分别为P < 0.001。疾病严重程度是预测COVID-19患者死亡率的唯一因素。在严重程度方面,年龄、厌食症、疲劳、胸膜炎、腹泻、发烧、出汗、呼吸短促和男性被确定为COVID-19患者严重程度的预测因素。随着年龄的增长,重症/危重症的发病率显著增加。年龄越大,死亡率越高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical features, severity, and outcomes of patients with COVID-19 infection: A follow-up study
Few epidemiological investigations explored disease outcomes in patients with COVID-19 in Iraqi Kurdistan. The association of clinical and epidemiological characteristics of COVID-19 patients with outcomes was examined in this study. Patients who were diagnosed with COVID-19 from a private clinic were followed up until recovery or death between 15th August and 20th October 2020. The mean age of the COVID-19 patients was 47.12 (6-90 years). Fatigue (76.15%), myalgia (66.53%), fever (65.33%), cough (62.53%), sweating (58.52%), and headache (56.11%) were the most prevalent symptoms. Most of the patients had mild severity (350, 70.14%) followed by moderate (74, 14.83%), severe (46, 9.22%), and critical (29, 5.81%). The case fatality rate (CFR) was 5.41% (n=27) and was significantly increased with increasing severity; mild (0.0%), moderate (1.35%), severe (10.87%), and critical (72.41%; P<0.001). The patients with the critical and severe situations were significantly older; medians: 67 vs 55 years compared to those patients with moderate and mild situations; medians: 51 vs 45 years; P<0.001. The patients who died were significantly older compared to recovered patients; medians: 65 vs 46 years; P<0.001, respectively. The disease severity was the only factor to predict mortality in patients with COVID-19 disease. Concerning the severity, being older, having anorexia, fatigue, pleurisy, diarrhea, fever, sweating, shortness of breath, and being male were determined to be predictors of severity in COVID-19 patients. The incidence rate of severe/critical conditions was significantly increased with increasing age. The older age was determined to be a predictor for higher mortality.
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