Juan J. Montero-Rodríguez, Edgar Eduardo Salazar-Flórez, P. Vega-Castillo, J. Tomasik, W. Galjan, K. M. Hafkemeyer, W. Krautschneider
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引用次数: 1
摘要
本文描述了一种用于生物样品阻抗谱的频率高达40 kHz的ASIC的设计和测试。该电路采用350 nm的AMS H35B4技术设计,可测量10 k W至28 M W的阻抗。该设计具有一个数字振荡器和一个电流-电压转换器。ASIC用于实时监测酵母细胞培养物和猪软骨细胞的生长,使用标准384孔板和铜电极。
An Impedance Spectroscopy ASIC for Low-Frequency Characterization of Biological Samples
: This paper describes the design and testing of an ASIC for impedance spectroscopy of biological samples at frequencies up to 40 kHz. The circuit is designed in the 350 nm AMS H35B4 technology and enables the measurement of impedances in the range of 10 k W up to 28 M W . The design features a digital oscillator and a current-to-voltage converter. The ASIC is used to monitor the growth of yeast cell cultures and porcine chondrocytes, in real-time, using a standard 384-well plate and copper electrodes.