盐浸/气发泡法制备PLLA支架

J. A. Riaño-Vélez, C. E. Echeverri-Cuartas
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引用次数: 0

摘要

生物可降解聚合物支架由于其在组织工程中作为修复材料或细胞粘附基质的潜力,近年来受到了越来越多的关注。这种材料的目的是修复或再生因疾病或创伤而受损的组织,提供一个时间结构,以促进细胞浸润和生长,提供相似的机械性能,避免流动性,免疫相容性和二次干预。我们通过盐浸/气体发泡法合成具有骨再生潜力的聚乳酸支架,并通过膨胀、压缩试验、扫描电镜和光学显微镜等技术对其进行形态学和力学表征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PLLA scaffold fabrication using salt leaching/gas foaming method
Biodegradable polymeric scaffolds have received considerable and increasing attention in the last past years due to their potential to be used in tissue engineering as a prosthetic material or cell adhesive substratum. This kind of material aims to repair or regenerate a tissue when it has been damaged through disease or trauma, providing a temporal structure to facilitate cellular infiltration and growth, provide similar mechanical properties and avoid mobility, immunocompatibility and secondary interventions. We work to synthesize a PLA scaffold with potential for bone regeneration produced by a salt leaching/gas foaming method and its respective morphological and mechanical characterization by techniques such as: swelling, compression assays, SEM and optical microscopy.
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