原发性肾小球肾炎的组织病理学模式-单中心经验

Shaheen Sikder, Faijul Islam, Mahmudur Rahman, Ehteshamul Hoque
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引用次数: 0

摘要

与其他发展中国家一样,肾小球肾炎是我国最常见的慢性肾脏疾病。我国原发性GN的发病率和组织学类型描述不充分。这项横断面前瞻性研究于2019年1月至2019年12月在孟加拉国达卡的三级保健教学医院神圣家族红新月医学院医院肾病科进行,包括所有接受肾脏活检的疑似原发性肾病患者。共行35例活检。M: F 1.3:1 .平均年龄33.71±12.2岁。膜增生性肾病(34.28%)是最常见的病因,其次是系膜增生性肾病(22.85%)、IgA肾病(17.14%)、膜性肾病(11.42%)、FSGS肾病(11.42%)和微小病变(2.8%)。35例中,20例有增生性真实。在免疫荧光研究中,19例有轻微到明显的免疫球蛋白沉积。5.71%的患者存在活检后并发症,但并不明显。由于样本量较小,因此需要更多的大规模研究来获得原发性GN的具体流行病学模式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Histopathological Pattern of Primary Glomerulonephritis - A Single Center Experience
lomerulonephritis is the most common cause of chronic kidney disease in our country like in other developing countries. The incidence and histological pattern of primary GN in our countare is inadequately described. This cross-sectional prospective study was conducted at the nephrology unit in Holy Family Red Crescent Medical College Hospital, a tertiary care teaching hospital in Dhaka, Bangladesh starting from January 2019 - December 2019 including all patients with suspected primary GN who underwent kidney biopsies. Total 35 biopsies were performed. M: F 1.3:1 .Mean age was 33.71+_12.2 yrs. Membranoproliferative GN (34.28%) was the most common cause followed by mesangioproliferative (22.85%), IgA nephropathy (17.14%), membranous (11.42%), FSGS ( 11.42%) and minimal change disease (2.8%). Among 35 cases, 20 had proliferative verity. In immunofluroscence study, 19 had mild to marked deposits of immunoglubulin. 5.71% had post-biopsy complication which was not significant enough. As the sample size was small so needs more studies in large to get the specific epidemiological patterns of primary GN.
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