两种不同技术经右开胸入路治疗心上部分肺静脉连接异常的远期疗效。前瞻性研究

Rashad Nuriyev, E. Hasanov, Faiq Mirzazade
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摘要

目的:本研究比较右开胸入路右肺静脉与上腔静脉部分异常连接的双补片和Warden手术的结果。材料与方法:选取年龄<18岁且右肺静脉与上腔静脉部分连接异常的患者100例,随机分为双补片法组(n=0)和Warden法组(n=50)。中位随访时间为31.5个月(范围10-45个月)。中期随访时主要终点为窦结功能障碍。结果:未发生早期或晚期死亡。术后早期,双补片技术和Warden手术分别有32.4%和7%的病例出现窦结功能障碍(风险比6.15;92%置信区间为1.45-26.35;p = 0.02)。在随访中,两名(5%)患者在双补片矫正后仍存在窦结功能障碍。所有患者在进行了Warden手术后窦性心律均恢复正常。两组均未发生早、晚起搏器植入。没有患者有明显的肺静脉或上腔静脉狭窄。结论:双补片法和Warden法均具有良好的中期疗效,无死亡。与双补片技术相比,Warden手术在术后早期出现的窦结功能障碍较少。中期随访时两组间窦结功能障碍无明显差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long-term results of two different techniques in patients with supracardiac partial anomalous pulmonary venous connection via right thoracotomy approach. A prospective study
Aim: This study compared outcomes following the double-patch and Warden procedures for correcting partial anomalous connection of the right pulmonary veins to the superior vena cava via right thoracotomy approach. Material and Methods: Hundred patients, aged <18 years old, and with partial anomalous connection of the right pulmonary veins to the superior vena cava were randomly selected into double-patch method (n=0) and Warden procedure (n=50) groups. The median follow-up was 31.5 (range, 10-45) months. The primary endpoint was sinus node dysfunction at the mid-term follow-up period. Results: No early or late mortality occurred. In the early postoperative period, sinus node dysfunction was observed in 32.4% and 7% of cases after double-patch technique and the Warden procedure, respectively (risk ratio, 6.15; 92% confidence interval, 1.45-26.35; p=0.02). At follow-up, sinus node dysfunction remained in two (5%) patients after double-patch correction. All patients had normal sinus rhythm after the Warden procedure. No early or late pacemaker implantation occurred in either group. No patients had significant pulmonary veins or superior vena cava stenosis. Conclusion: The double-patch technique and Warden procedure both showed best mid - term consequences without mortality. The Warden procedure was linked with less sinus node dysfunction in the early postoperative period than the double-patch technique. There was no significant various differences in sinus node dysfunction at the mid-term follow-up.
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