用于生化IC系列的SMA微型泵和开关阀

K. Ikuta, T. Hasegawa, T. Adachi
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引用次数: 6

摘要

基于集成电路芯片组家族的概念,提出并开发了一种多功能微流控装置“生化集成电路家族”。目前已经开发了几种包含反应器、浓缩器和单向阀等多个微流体装置的生化集成电路,并利用这些芯片合成了萤火虫发光酶。由于以往的实验中所有的化学流体都是由外部泵供给的,因此整个IC家族都需要微型泵芯片和开关阀芯片。本研究首次成功制备了处理化学流体的新型芯片,并对其基本性能进行了实验验证。采用形状记忆合金(SMA)微致动器进行微致动。开发了一种新的微立体光刻工艺(Hybrid IH工艺),用于制作由UV聚合物和其他微部件组成的三维复合结构,并将其用于全芯片制造。微型泵芯片成功地通过连接的芯片提供化学液体。另一方面,微开关阀芯片改变反应通过迅速。通过使用这些生化IC芯片,化学家可以在自己的实验室中构建各种反应体系的新时代即将到来。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SMA micro pumps and switching valves for biochemical IC family
A versatile micro fluidic device "Biochemical IC Family" based on the concept of IC chip-set family has been proposed and developed by the authors. Several types of biochemical IC containing multiple micro fluidic devices such as reactors, concentrators and one-way valves have been already developed and we have demonstrated that a luminous enzyme of firefly was synthesized by using these chips. Since all chemical fluids were supply by the external pumps in the past experiment, the micro pump chip and switching valve chip are demanded for total IC family. In this research, new chips to handle chemical fluid were first fabricated successfully and basic performance was verified experimentally. Shape memory alloy (SMA) micro actuator was utilized for micro actuation. A new micro stereo lithography process (Hybrid IH Process) to make 3D composite structures consisting of UV polymer and other micro parts was developed and was utilized for total chip fabrication. The micro pump chip succeeded to supply chemical liquids through the connected chips. On the other hand, the micro switching valve chip changed reaction passes quickly. By using these biochemical IC chips, a new era where various kinds of reaction systems can be constructed by chemists in their own laboratory will come.
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