Sora Tomita, Terumasa Ito, Kazuyuki Iwaikawa, G. Hayase, D. Yoshino, K. Misawa
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Quantitative measurement of low-concentration analytes using Raman spectroscopy during droplet evaporation for therapeutic drug monitoring
We propose a new method for therapeutic drug monitoring using Raman spectroscopy to quantify the concentration of analytes during droplet evaporation. The proposed method is demonstrated for quantitative measurement of methotrexate down to 0.5 mM.
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