{"title":"病例报告:垂体腺瘤残留患者低皮质醇和甲状腺功能减退的术前激素替代治疗","authors":"Huwainan Nisa Nasution","doi":"10.30596/BF.V6I1.5636.G5255","DOIUrl":null,"url":null,"abstract":"Pituitary tumors are benign tumors that occur in the pituitary gland with a presentation of 10% of all intracranial tumors. If the size of the tumor is > 1 cm, the pituitary tumor is called a macroadenoma, the large size will have a mass effect so that there is an emphasis on the tumor area and its surroundings. This emphasis will manifest in hyposecretion of the hormones produced in the pituitary. We report a case of 57-year-old male with complaints of decreased vision since 3.5 months. The patient had previously been diagnosed with a pituitary tumor 6 years ago and had surgery. After diagnostic steps, the patient is diagnosed with a residual pituitary adenoma tumor with hypocortisol and hypothyroidism. Hormone replacement therapy was performed by administering methilprednisolone tablets 16 mg-0-8 mg and levothyroxine tablets 1 x 50 µg. The patient was planned to undergo an Endoscopic Endonasal Excision Tumor surgery with 125 mg/12 hour preoperative injection of methilprednisolon. The provision of preoperative hormone replacement therapy aims to correct hormonal imbalances that can be an intraoperative complication","PeriodicalId":206231,"journal":{"name":"Buletin Farmatera","volume":"75 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Case Report: Preoperative Hormone Replacement Therapy in Hypocortisol and Hypothyroid Patients with Residual Pituitary Adenoma Tumors\",\"authors\":\"Huwainan Nisa Nasution\",\"doi\":\"10.30596/BF.V6I1.5636.G5255\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Pituitary tumors are benign tumors that occur in the pituitary gland with a presentation of 10% of all intracranial tumors. If the size of the tumor is > 1 cm, the pituitary tumor is called a macroadenoma, the large size will have a mass effect so that there is an emphasis on the tumor area and its surroundings. This emphasis will manifest in hyposecretion of the hormones produced in the pituitary. We report a case of 57-year-old male with complaints of decreased vision since 3.5 months. The patient had previously been diagnosed with a pituitary tumor 6 years ago and had surgery. After diagnostic steps, the patient is diagnosed with a residual pituitary adenoma tumor with hypocortisol and hypothyroidism. Hormone replacement therapy was performed by administering methilprednisolone tablets 16 mg-0-8 mg and levothyroxine tablets 1 x 50 µg. The patient was planned to undergo an Endoscopic Endonasal Excision Tumor surgery with 125 mg/12 hour preoperative injection of methilprednisolon. The provision of preoperative hormone replacement therapy aims to correct hormonal imbalances that can be an intraoperative complication\",\"PeriodicalId\":206231,\"journal\":{\"name\":\"Buletin Farmatera\",\"volume\":\"75 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-02-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Buletin Farmatera\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30596/BF.V6I1.5636.G5255\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Buletin Farmatera","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30596/BF.V6I1.5636.G5255","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
垂体瘤是发生在脑垂体的良性肿瘤,占颅内肿瘤的10%。如果肿瘤的大小大于1cm,则称为垂体大腺瘤,大的尺寸会产生肿块效应,使肿瘤区域及其周围环境受到重视。这种强调将表现为垂体产生的激素分泌减少。我们报告一例57岁男性,自3.5个月以来视力下降。患者6年前曾被诊断为垂体瘤并进行了手术。经过诊断步骤,患者被诊断为残留垂体腺瘤肿瘤伴低皮质醇和甲状腺功能减退。激素替代治疗采用甲泼尼龙片16 mg-0-8 mg和左旋甲状腺素片1 x 50µg。患者计划行内镜下鼻内切除肿瘤手术,术前注射甲泼尼松125mg /12小时。术前激素替代治疗旨在纠正可能成为术中并发症的激素失衡
Case Report: Preoperative Hormone Replacement Therapy in Hypocortisol and Hypothyroid Patients with Residual Pituitary Adenoma Tumors
Pituitary tumors are benign tumors that occur in the pituitary gland with a presentation of 10% of all intracranial tumors. If the size of the tumor is > 1 cm, the pituitary tumor is called a macroadenoma, the large size will have a mass effect so that there is an emphasis on the tumor area and its surroundings. This emphasis will manifest in hyposecretion of the hormones produced in the pituitary. We report a case of 57-year-old male with complaints of decreased vision since 3.5 months. The patient had previously been diagnosed with a pituitary tumor 6 years ago and had surgery. After diagnostic steps, the patient is diagnosed with a residual pituitary adenoma tumor with hypocortisol and hypothyroidism. Hormone replacement therapy was performed by administering methilprednisolone tablets 16 mg-0-8 mg and levothyroxine tablets 1 x 50 µg. The patient was planned to undergo an Endoscopic Endonasal Excision Tumor surgery with 125 mg/12 hour preoperative injection of methilprednisolon. The provision of preoperative hormone replacement therapy aims to correct hormonal imbalances that can be an intraoperative complication