Contrast enhancement in OSEM reconstruction-2002 IEEE nuclear science symposium and medical imaging conference

Iterative algorithms offer many advantages over filtered backprojection reconstruction. These include diminishing of streak artifacts, less sensitivity to missing projections and the ability to incorporate accurate corrections for spatial resolution, scatter and attenuation. However, in studies where the count density is relatively high, e.g. F-18 FDG brain studies, more iterations are required to achieve comparable contrast with filtered backprojection reconstructed images. In this paper we present a method for achieving high contrast reconstructed images using an iterative algorithm without increasing the iteration number.