基于硬件加速器的DNA序列匹配系统在多线程环境下的高效利用

F. Khan, Aurangzeb, Z. Khan
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引用次数: 1

摘要

生物信息学已经成为这样一门科学:如果有道德地利用知识,就会给人类带来普遍的利益。DNA链数据的巨大量已被揭示为巨大的比例。为了处理如此庞大的数据量,必须采用并行和分布式超级计算技术。我们已经部署了一个可扩展的线性连接硬件加速器阵列,用于解决史密斯-沃特曼算法;一种用于解决DNA链序列比对的技术。我们在一个可重构平台上对系统进行了综合,并对所完成的加速系数进行了性能分析。该系统进一步连接到一个强大的嵌入式微处理器,该微处理器在多线程环境中充当万维网的接口。这一努力是为了将高性能计算,在这一领域,以一种经济有效的方式带到科学家和爱好者的家门口,从而引发大量的发现,并为这一领域的科学工作提供急需的动力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
DNA sequence matching system based on hardware accelerators utilized efficiently in a multithreaded environment
Bio Informatics has emerged as one of those sciences in which if knowledge, if exploited ethically, will result in the general benefit of mankind. The enormity of DNA strand data has been revealed to be of humongous proportions. It is imperative to employ the art of parallel and distributed supercomputing in order to process such magnanimous magnitudes of data. We have deployed a scalable array of linearly connected hardware accelerators for the solution of the Smith-Waterman Algorithm; a technique used to resolve sequence alignment of DNA strands. We have synthesized the system on a reconfigurable platform and carried out a performance analysis of the speedup factor accomplished. The system is further connected to a powerful embedded microprocessor which, in a multithreaded environment, serves as an interface to the World Wide Web. This effort is in a bid to bring High-Performance Computing, in this domain, to the doorstep of scientists and enthusiasts alike in a cost-effective manner, thereby, triggering an avalanche of discoveries and providing much needed impetus to scientific work in this area.
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