在西孟加拉邦的一家三级医院处理败血性流产

S. Hazra, P. Sarkar, A. Chaudhuri, G. Mitra, D. Banerjee, Sarmistha Guha
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引用次数: 6

摘要

背景:败血性流产仍然是一个具有挑战性的问题,也是发展中国家孕产妇死亡和发病的主要原因。目的:本研究旨在估计西孟加拉邦三级卫生保健机构脓毒性流产病例的发生率、原因、危险因素、相关微生物和治疗方式。对象与方法:本研究于2011年7月至2012年6月在西孟加拉邦的布尔德万医学院和医院进行交叉截面研究。入院时,要详细记录病史,进行检查和调查。根据检查结果将病例分为三级:一级:感染局限于子宫;II级:感染扩散到子宫外的参数、输卵管、卵巢或盆腔腹膜;III级:全身性腹膜炎和/或内源性休克或黄疸或急性肾功能衰竭。将所有数据以表格形式整理,以简单百分比表示后,采用Epi Info™软件(Version 3.5.1, CDC)进行统计分析。结果:本院住院1297例流产,其中感染性流产107例,感染性流产发生率为8.2%(107/1297)。40.3%(46/107)脓毒性流产为1级,21.5%(23/107)为2级,35.5%(38/107)为3级。患者的模态年龄为15 ~ 25岁(49.5%)。大多数受试者已婚(77.6%);83/107)和多产(60.7%;65/107)。同样,大多数人(71%;76/107)来自低社会经济阶层。90%(96/107)的患者进行了人工流产。常见临床表现为面色苍白(88.8%);95/107)和发热(86.0%;92/107)。大肠杆菌(62.6%;67/107)和肺炎克雷伯菌(32.75%;35/107)是最常见的分离菌。在本研究中,败血性流产的病死率为13.1%,占回顾期间孕产妇总死亡率的15.4%。结论:本研究中败血性流产的发生率较高,且以试图终止妊娠为主。它是造成产妇死亡率的一个重要因素。促进计划生育和使堕胎服务合法化将大大有助于减少败血性流产及其相关并发症的发生率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Septic abortion managed in a tertiary hospital in West Bengal
Background: Septic abortion is still a challenging problem and a major cause of maternal mortality and morbidity in developing countries. Aim: The present study was conducted to estimate incidence, causes, risk factors, associated microorganisms, and treatment modalities of cases of septic abortion managed in a tertiary health care in West Bengal. Subjects and Methods: It was a cross‑sectional study carried out in Burdwan Medical College and Hospital in West Bengal between July 2011 and June 2012. On admission a thorough history was taken, examination was done, and investigations were carried. Depending on the examination findings the cases were grouped into three grades‑grade I: The infection localized in the uterus; grade II: The infection spread beyond the uterus to the parametrium, tubes, and ovaries or pelvic peritoneum; grade III: Generalized peritonitis and/or endotoxic shock or jaundice or acute renal failure. Statistical analysis was done by using Epi Info™ software (Version 3.5.1, CDC) after proper arrangement of all the data in tabular form and presented as simple percentage. Results: During the period, 1297 cases of abortion were admitted among which 107 were septic abortions, thus giving the incidence of the latter as 8.2% (107/1297). Forty‑three percent cases of septic abortion (46/107) were in grade I, 21.5% (23/107) in grade II, and 35.5% (38/107) in grade III. The modal age group of the patients was 15‑25 years (49.5%). Majority of the subjects were married (77.6%; 83/107) and multiparous (60.7%; 65/107). Similarly, most of them (71%; 76/107) were from low socioeconomic class. Ninety percent of the patients (96/107) had induced abortion. The common clinical features at presentation were pallor (88.8%; 95/107) and fever (86.0%; 92/107). Escherichia coli (62.6%; 67/107) and Klebsiella pneumonia (32.75%; 35/107) were the most common organism isolated. The case fatality from septic abortion in this study was 13.1% and the condition accounted for 15.4% of total maternal mortality within the period reviewed. Conclusion: The incidence of septic abortion in this study is relatively high, and majority of the cases resulted from attempted termination of pregnancy. It is a significant contributor to maternal mortality. Promotion of family planning and legalization of abortion services will go a long way in reducing the incidence of septic abortion and its associated complications.
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