用于癌症治疗的非线性传输线射频脉冲发生器的研制

Y. Abe, Y. Minamitani
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引用次数: 5

摘要

纳秒级和亚纳秒级高压脉冲可以提供新的应用。利用超短脉冲高电场治疗癌症就是其中之一。提出了用高功率脉冲电磁波施加高电场对其进行处理。本工作的重点是利用纳秒脉冲功率发生器设计一种用于癌症治疗的紧凑型高功率脉冲电磁波发生器。在之前的研究中,我们使用了LC逆变电路作为脉冲电磁波发生器的电源。为了使天线有效地输出电磁波,LC逆变电路是有用的。但由于LC逆变电路输出的电压波形带有阻尼振荡,因此突发脉冲的持续时间在100ns以下。因此,我们重点研究了一种填充铁氧体铁芯的同轴非线性传输线。NLTL能够产生高频的接触脉冲波。与其他采用非线性元件的NLTL相比,非线性共轴线具有结构简单、成本低等优点。因此,我们研究了利用铁氧体填充同轴非线性传输线的突发脉冲发生器,以延长突发振荡的持续时间,用于癌症治疗。在实验中,研究了不同输入脉冲形状和磁芯条件下NLTL输出脉冲的脉冲持续时间和频率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Development of a RF burst pulse generator using a non-linear transmission line for cancer treatment
Nanosecond and sub-nanosecond high voltage pulses can provide new applications. A cancer treatment by an ultra-short pulse high electric field is one of them. High power pulse electromagnetic wave has been proposed to apply the high electric field for that treatment. This work focuses on the design of a compact high power burst pulse electromagnetic wave generator using a nanosecond pulsed power generator for the cancer treatment. In previous study, we have used a LC inversion circuit as a power supply of the pulse electromagnetic wave generator. The LC inversion circuit is useful in order to output efficiently electromagnetic wave by the antenna. However, since the LC inversion circuit outputs the voltage waveform with damping oscillation, the duration of the burst pulse is under 100ns. Therefore, we focus on a coaxial nonlinear transmission line (NLTL) filled with ferrite cores. NLTL is capable of generating the high frequency osculation pulse wave. The non-linear coaxial line has the advantage of simple structure and low cost in comparison with the other NLTL using a non-linear element. Therefore we have investigated the burst pulse generator using the ferrite-filled coaxial non-linear transmission line in order to extend the duration of the burst oscillation for the cancer treatment. In the experiment, the pulse duration time and frequency of the output pulse of the NLTL for various conditions of the input pulse shape and the magnetic cores were investigated.
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