早产儿半无水脑畸形1例报告

Tijana Prodanovic, Suzana Živojinović
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引用次数: 0

摘要

无脑畸形是一种罕见的中枢神经系统异常,其特征是脑实质缺失,取而代之的是充满脑脊液、胶质组织和室管膜的膜性囊。当表现为半无水脑畸形时,患者预后较好。我们提出了一例早产儿与双胎妊娠半无水脑畸形,有一个致命的结果。在控制妊娠早产婴儿在31周孕龄分娩。该新生儿的母亲因sars - 19检测呈阳性而在传染病诊所住院。在紧急剖腹产后,使用快速抗原和PCR检测对新生儿进行了Covid - 19检测,结果为阴性。在产房,对婴儿进行触觉刺激、抽吸、正压通气后插管。插管后,进行手工心脏按摩,之后检测心脏活动和呼吸运动。”三小时后,心肺骤停,复苏失败。另一个双胞胎出生时没有异常,但出现了呼吸窘迫综合征的迹象。尸检显示右半球有一个薄壁腔,腔内充满透明的淡黄色液体。记录新生儿无脑畸形的病例对父母关于生存时间、妊娠成功管理和产前诊断程序的表现的咨询非常重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hemihydranencephaly of Premature Infant - Case Report
Abstract Hydranencephaly represents a rare anomaly of the central nervous system and is characterized by the parenchymal absence which is replaced with a membranous sac filled with cerebrospinal liquid, glial tissue and ependyma. When it is manifested as hemihydranencephaly, the patient’s prognosis is better. We presented a case of a premature infant with hemihydranencephaly in twin pregnancy that had a fatal outcome. A premature infant in a controlled pregnancy was delivered at 31 weeks of gestational age. The mother of the newborn was hospitalized in the Clinic for Infective Diseases since she had tested positive for SARS-Covid- 19. Following an urgent Caesarean section, the newborn was tested for Covid 19 using the rapid antigen and PCR test and the results were negative. In the delivery room, the tactile stimulation, aspiration, positive pressure ventilation of the infant were applied, after which it was intubated. After the intubation, a manual heart massage was performed, after which the cardiac activity and agonal breathing movements were detected.” Three hours later, cardiorespiratory arrest happened, following unsuccessful resuscitation. The other twin was born with no anomalies, but showed signs of respiratory distress syndrome. Autopsy revealed that there was a thin-walled cavity filled with clear, yellowish liquid in the right hemisphere. Documenting cases of newborns with hydranencephaly is of a great importance for counseling parents regarding length of survival, successful management of pregnancy, and performance of prenatal diagnostic procedures.
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