金黄色葡萄球菌耐药机制的研究与新抗生素的研究

Atamjit Singh, Kirandeep Kaur, P. Mohana, Avneet Kaur, K. Kaur, Shilpa Heer, Saroj Arora, Neena Bedi, P. Bedi
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引用次数: 1

摘要

金黄色葡萄球菌是环境和动物中最普遍存在的微生物,以共生菌和致病菌的形式存在。在过去的几年里,它已经成为一种超级细菌,给医疗系统造成了严重的负担。由于其快速的结构和基因修饰,这种细菌已被发现对大多数抗生素具有最强的耐药性。本章将阐明金黄色葡萄球菌耐药的各种分子机制,展示它是如何作为一种超级细菌出现的。此外,本文还讨论了近年来的研究方法,包括探索不同的药物靶点,同时考虑金黄色葡萄球菌的结构和功能行为。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mechanistic Insights of Drug Resistance in Staphylococcus Aureus with Special Reference to Newer Antibiotics
Staphylococcus aureus is the most ubiquitous microorganism in both environment as well as animals and exists as commensal and pathogenic bacterium. In past few years it has been emerged as a superbug causing serious burden on healthcare system. This bacterium has been found to be the most resistant one toward most of the antibiotics due to its rapid structural and genetic modifications. This chapter will shed light on various types of molecular mechanisms responsible for resistance of Staphylococcus aureus showcasing how it has been emerged as a superbug. Moreover, the recent approaches which include exploring of different drug targets keeping in view the structural and functional behavior of the Staphylococcus aureus has also been discussed.
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