多囊卵巢综合征Asprosin水平的测定及其与胎儿素a及一些生化指标的关系

Balasim J Mahmmoed, N. Hilal, E. Sarhat
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引用次数: 0

摘要

卵巢囊肿是一种常见的荷尔蒙疾病,影响育龄妇女和卵巢。虽然确切的病因尚不清楚,但环境和遗传变量可能在该病的发生中起作用。其中最显著的症状是月经不调、毛发过度生长和痤疮。早期诊断至关重要,因为它可以帮助控制症状,并可能防止慢性疾病的发展。本研究的目的是评价多囊卵巢综合征患者阿泌素的水平及其相关性。女性多囊卵巢综合征患者血凝素、胎儿素a与空腹血糖、胰岛素、胆固醇、甘油三酯等生化指标的关系研究招募了90名女性;选取60例年龄在15-45岁之间的女性和经妇科专家诊断为多囊卵巢的女性。结果是负责排卵的激素,如LH, FSH,以及蛋白asprosin和胎蛋白a的增加。另一方面,30人作为对照组(女性),他们的年龄也感染了多囊卵巢综合征,但没有感染。对两组进行了实验室测试,以确定阿泌素、胎儿蛋白a、空腹血糖、胰岛素、总胆固醇和甘油三酯的水平。该研究对专利和对照组进行了asprosin分析。比较时p值=0.115,结果无统计学意义。还进行了Fetuin分析。两组患者与健康对照组的结果比较,p值=0.0002,差异有显著统计学意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation Asprosin Level in Polycystic Ovary Syndrome and Its Association with Fetuin a and Some Biochemical Parameter
An ovarian cyst is a common hormonal condition that affects women of reproductive age and affects the ovaries. Although the precise an etiology is unknown, environmental and genetic variables may play a role in the condition's genesis. Among the most significant symptoms are irregular menstruation, excessive hair growth, and acne. Early diagnosis is crucial since it can help control symptoms and possibly save chronic medical conditions from developing. The aim of this study was to evaluate the levels and relation of asprosin in patients of polycystic ovary syndrome. the relationship between asprosin with fetuin a and some parameter biochemical such as fasting blood sugar, insulin, cholesterol and triglyceride in woman patient’s polycystic ovary syndrome. Ninety females were recruited into the study; 60 patients (females) aged between (15-45) years were taken and women that diagnosed with the Polycystic ovaries, by gynecological specialist. The result was a disruption in the hormones responsible for ovulation, such as LH, FSH, as well as an increase in the protein asprosin and fetuin a. On the other hand, 30 people as a control group of (females) were taken and their ages were also and were not infected with polycystic ovary syndrome. Laboratory tests were conducted for both groups to determine the level of asprosin, fetuin a, fasting blood sugar, insulin, total cholesterol and triglyceride. the study conducted a asprosin analysis for patents and a control group. When comparing the results were statistically no significant at P. value =0.115. Also conducted a Fetuin an analysis. When comparing the results of these two groups of patients and healthy controls, the results were statistically highly significant at P. value =0.0002.
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