L. Chulenbayeva, S. Kashanskiy, Kenzhekyz B. Manekenova, G. Ilderbayeva, Talgat M. Omarov, O. Ilderbayev
{"title":"氧化应激环境中粉尘和辐射联合暴露的致癌和遗传毒性风险","authors":"L. Chulenbayeva, S. Kashanskiy, Kenzhekyz B. Manekenova, G. Ilderbayeva, Talgat M. Omarov, O. Ilderbayev","doi":"10.31089/1026-9428-2018-11-60-64","DOIUrl":null,"url":null,"abstract":"Rats subjected to coal dust combined with radiation dose of 6 Gy in long-term period demonstrated cytogenetic disorders and changes in bronchial mucosa, arterial and arterioli walls in lung stroma, destructive changes in liver parenchyma with colliquation necrosis foci in liver lobules, on oxidative stress background. Findings are that combined experimental exposure to dust and radiation on oxidative stress background increases carcinogenic and genotoxic risks in animals.","PeriodicalId":229714,"journal":{"name":"Occupational Health and Industrial Ecology","volume":"64 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Carcinogenic and genotoxic risks of combined exposure to dust and radiation in oxidative stress environment\",\"authors\":\"L. Chulenbayeva, S. Kashanskiy, Kenzhekyz B. Manekenova, G. Ilderbayeva, Talgat M. Omarov, O. Ilderbayev\",\"doi\":\"10.31089/1026-9428-2018-11-60-64\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Rats subjected to coal dust combined with radiation dose of 6 Gy in long-term period demonstrated cytogenetic disorders and changes in bronchial mucosa, arterial and arterioli walls in lung stroma, destructive changes in liver parenchyma with colliquation necrosis foci in liver lobules, on oxidative stress background. Findings are that combined experimental exposure to dust and radiation on oxidative stress background increases carcinogenic and genotoxic risks in animals.\",\"PeriodicalId\":229714,\"journal\":{\"name\":\"Occupational Health and Industrial Ecology\",\"volume\":\"64 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-02-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Occupational Health and Industrial Ecology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31089/1026-9428-2018-11-60-64\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Occupational Health and Industrial Ecology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31089/1026-9428-2018-11-60-64","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Carcinogenic and genotoxic risks of combined exposure to dust and radiation in oxidative stress environment
Rats subjected to coal dust combined with radiation dose of 6 Gy in long-term period demonstrated cytogenetic disorders and changes in bronchial mucosa, arterial and arterioli walls in lung stroma, destructive changes in liver parenchyma with colliquation necrosis foci in liver lobules, on oxidative stress background. Findings are that combined experimental exposure to dust and radiation on oxidative stress background increases carcinogenic and genotoxic risks in animals.