Comparative study of intrathecal (1%) 2-Chloroprocaine Vs intrathecal (0.5%) Sensorcaine for day care surgeries

Background: Day-care surgery, it is the patient being discharged from the hospital on the same day of surgical procedure, has become immensely popular modality of treatment throughout the globe. Aims and Objectives: To compare the efficacy of intrathecal (1%) 2-Chloroprocaine and intrathecal (0.5%) sensorcaine for day care infraumbilical surgeries. Methodology: This was a prospective, randomized study carried out in the patients undergoing the various infraumbilical day care surgeries under spinal anaesthesia at tertiary health care centre. After the ethical permission, the written informed consent was obtained from 70 patients and was enrolled in the study. Out of 70 patients, 35 patients were enrolled to Group A i.e. Chloroprocaine Group and 35 patient in Group B i.e. Sensorcaine Group The patients were randomly allocated in to the groups by computer generated random numbers. . The subarachonoid block was given to the patients in Group A with (1% ) 50 mg chlorprocaine and in Group B with( 0.5% ) 15 mg sensorcaine. The data was then analyzed by unpaired t-test and chi-square test by SPSS 19 version software. Results: The mean age in both the groups were comparable i.e. 34 ± 4.65 35± 3.97 (t=0.76,df=48,P>0.05) and the Male to Female ratio was also comparable i.e. 2.5 :1 and 1.67:1 (X2=0.35,df=1,p>0.05). Time for onset of Sensory block(min) was comparable in both the groups was 2.45 ± 1.03 and 2.29 ± 0.93 (P>0.05,t=0.72,df=68); Time for onset of Motor block (min) was comparable i.e. 3.1± 0.34 and 2.84 ± 1.04 (P >0.05,t=0.92,df=68); Total duration of sensory block (min) was significantly higher in group B ( 167 ±43.87) than Group A (105.62±30.56), (P<0.05,t=4.92,df=68); Total duration of motor block (min) was significantly greater in Group B(135±54.32) than Group A (95.73± 30.76), (P<0.05,t=1.02,df=68). Conclusion: It can be concluded from this study that sensorcaine was superior to chloroprocaine with respect to sensory motor blockade otherwise it was comparable in all the other characteristics of anaesthesia.