抗疫血浆对重症监护病房患者COVID-19的影响

O. N. Yamshikov
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引用次数: 0

摘要

SARS-CoV-2病毒的传播及其导致的死亡率上升,促使人们寻找和评估针对患者的现有药物治疗方法,特别是针对那些在COVID - 19医院重症监护病房的患者。冠状病毒感染过程的一个特点是其不可预测的性质和严重程度。在这方面,有必要使用有针对性和强大的病理治疗手段。由于缺乏针对COVID-19的特异性治疗方法,人们想到了被动免疫治疗的可能性,首先通过输入恢复期供体血浆,然后输入接种疫苗个体的血浆。这种治疗的目的是将covid抗体引入受体的血液中以中和病毒。与此同时,这种治疗方法对新冠中心重症监护病房重症和极重症患者的有效性仍然存在疑问。根据各种研究,抗covid - 19血浆适用于处于疾病初始阶段和患者存在免疫缺陷的患者。与此同时,重症监护病房和重症、极重症患者的总体死亡率可能不会下降。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of anticovid plasma on COVID-19 among patients in intensive care unit of COVID hospital
The spread of the SARS-CoV-2 virus and the increased mortality caused by it has led to the search and evaluation of available methods of drug therapy for patients, especially those who are in intensive care units of COVID hospitals. A feature of the course of coronavirus infection is its unpredictable nature and severity. In this regard, it became necessary to use targeted and powerful means of pathogenetic therapy. The lack of a specific treatment for COVID-19 brought to mind the possibility of passive immunotherapy, first through the transfusion of convalescent donor plasma, and then the plasma of vaccinated individuals. The purpose of such therapy is to introduce covid antibodies into the recipient's blood to neutralize the virus. At the same time, the question remains about the effectiveness of this treatment method in patients in serious and extremely serious condition in the intensive care unit of the COVID center. According to various studies, anticovid plasma is suitable for use in patients at the initial stages of the disease and in the presence of immunodeficiency in the patient. At the same time, the overall mortality in the intensive care unit and intensive care among severe and extremely severe patients may not decrease.
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