N. Reddy, Sadu Nageswara Rao, R. Patil, S. Adimurthy
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Transition metal-free hydration of nitriles to amides mediated by NaOH
A transition metal-free NaOH mediated hydration of organo nitriles to amides under mild reaction conditions has been described. Both aliphatic and aromatic/hetero nitriles were smoothly converted into corresponding amides in moderate to good yields. *Correspondence to: Subbarayappa Adimurthy, Central Salt & Marine Chemicals Research Institute, Council of Scientific & Industrial Research, G.B. Marg, Bhavnagar-364 002, Gujarat, India, Fax: +91-278-2567562; E-mail: adimurthy@csmcri.res.in