时空波束形成微波成像用于乳腺癌检测的实验研究

Xu Li, S. Hagness, B. V. Van Veen, Daniel W Van Der Weide
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引用次数: 41

摘要

我们研究了利用时空波束形成的微波成像方法检测乳腺小恶性肿瘤的实验可行性。一个由紧凑的超宽带(1- 11ghz)天线组成的平面合成阵列组成的微波传感器被放置在乳房组织幻象之上——乳房组织幻象是由一层薄薄的皮肤模拟物覆盖的均匀的正常乳房组织模拟物。一个小的(< 0.5厘米)的合成肿瘤嵌入乳房假体。在阵列的每个位置,天线将合成的超短脉冲传输到乳房幻象中。鲁棒的数据自适应算法消除了由皮肤-乳房界面的主要反向散射引起的伪影。信号通过一个三维时空波束形成器,该波束形成器被设计成根据位置对后向散射能量进行成像。由于与正常乳腺组织相比,毫米级的恶性肿瘤具有显著的介电特性,因此其微波散射截面也相对较大。因此,它们在波束形成器图像中产生大后向散射能级的局部区域。成功的检测和定位非常小的合成肿瘤嵌入皮肤乳房组织幻影证明。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Experimental investigation of microwave imaging via space-time beamforming for breast cancer detection
We investigate the experimental feasibility of detecting small malignant breast tumors using a recently proposed method of microwave imaging via space-time beamforming. A microwave sensor comprised of a planar synthetic array of compact ultrawideband (1-11 GHz) antennas is placed above a breast tissue phantom - a tank of homogeneous normal breast tissue simulant covered by a thin layer of skin simulant. A small (< 0.5 cm) synthetic tumor is embedded in the breast phantom. At each position in the array, the antenna transmits a synthetically generated ultra-short pulse into the breast phantom. A robust data-adaptive algorithm removes the artifact caused by the dominant backscatter from the skin-breast interface. The signals are passed through a 3-D space-time beamformer designed to image backscattered energy as a function of location. Even millimeter-sized malignant tumors have relatively large microwave scattering cross-sections due to their significant dielectric-properties contrast with normal breast tissue. Therefore they produce localized regions of large backscatter energy levels in the beamformer image. The successful detection and localization of very small synthetic tumors embedded in the skin-breast tissue phantom is demonstrated.
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