A 64-site Multiplexed Low-profile Neural Probe With On-chip Cmos Circuitry

This paper describes a micromachined CMOS probe for multisite stimulation and recording in the central nervous system. The probe uses flexible silicon interconnects to allow the signal processing circuitry to fold at right anglcs to the probe shanks, limiting the implanted profile above thc cortex to llmm while driving any 8 of the 64 sites with 0 to k127p.A f1p.A. An on-chip amplifier allows the neural activity on any selected site to be recorded with an overall gain of 50 and bandwidth from 50Hz to 7kHz. Micropower circuit techniques allow the probe to dissipate 4Op.W in standby from f5V.