Changes with the Smell Associated with Hypogonadotropic Hypogonadism the Importance of an Early Detection

Introduction: The hypogonadotropic hypogonadism associated with disturbances of smell (HHAAO), is a variant of hypogonadotropic hypogonadism, which are associated to a defect in the pituitary or hypothalamus, caused by a lack of hormones which used to stimulate the ovaries or the testicles. Clinical Case: Based on patients who consulted for disorders of smell, from October 2013 to October 2014, 30 patients aged 6-16 years were detected, 3 women under 15 years old; they had anosmia that were proven by olfactometry and absence of olfactory bulbs in Nuclear Magnetic Resonance. One patient had lost of hearing too. Discussion: The study protocol consist of: complete anamnesis, smell test, Nuclear Magnetic Resonance Solid craniofacial smell protocol, hormonal assay of LDH and basal FSH, Serviced inter consultation Pediatrics and Endocrinology. In addition, audiometric studies, abdominal ultrasound and molecular genetics to diagnosis.