Evaluation of variation in dimensions of sella turcica in patients with unilateral cleft lip and palate as compared to Class I controls

The cleft of the lip and palate is the most common congenital anomaly affecting the cranio-facial region [1,2]. The etiology of CLP is said to be multi-factorial having both genetic and environmental causes. Clefts may be localized defects or may be associated with widespread structural changes in other parts of the skull [3]. Several studies have shown that the growth and displacement of the maxilla is directly linked to the growth and angulation of the cranial base [4-6]. Hence it may be assumed that any anomaly in the cranial base may have impact on the growth as well as spatial position of the naso-maxillary complex.