M. Lugos, Bitrus N. Lekshak, Changjul L. Singnap, U. Polit, Benedict H Mangs
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Following informed consent, we determined haematocrit values by the microhaematocrit method, haemoglobin (Hb) concentration by cyanmethaemoglobin technique, total and differential white blood cell counts (WBC), malaria parasite as well as microscopic blood film reporting of 124 alcohol consumers and 53 non-consumers as a control. SPSS version 23 was used to compare mean values between alcohol consumers and the control group (student t-test), while associations of blood film report were determined by chi-square. Results showed a significantly higher total lymphocytes count among alcohol consumers compared to nonalcohol consumers (48.28±12.98 v 41.91±11.59; p=0.002). Also, the blood film reporting revealed a significantly higher percentages of macrocytes (p=0.001), microcytes (p=0.020), hypochromia (p=0.001), polychromasia (p=0.013), rouleaux formation (p=0.004) and atypical lymphocytes (p=0.011) and malaria parasitaemia (p=0.001) among alcohol consumers compared to the control group. 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引用次数: 1
摘要
酒精饮料中含有乙醇,酒精饮料是由谷物、水果和其他糖源发酵而成的。青少年和成年人饮酒导致社会犯罪率上升的影响引起了人们的极大关注。在乔斯大都会,酒精消费对血液学变量的影响尚未得到很好的记录。这项研究试图确定饮酒是否对个人的血液学状况有任何影响。根据知情同意,我们通过微红细胞压积法测定红细胞压积值,通过氰化血红蛋白技术测定血红蛋白(Hb)浓度,总白细胞计数和差异白细胞计数(WBC),疟疾寄生虫以及显微镜血膜报告124名饮酒者和53名非饮酒者作为对照。使用SPSS 23版本比较酒精消费者与对照组的平均值(学生t检验),血膜报告的相关性采用卡方检验。结果显示,饮酒者的总淋巴细胞计数明显高于非饮酒者(48.28±12.98 v 41.91±11.59;p = 0.002)。此外,血膜报告显示,与对照组相比,酒精消费者中巨细胞(p=0.001)、小细胞(p=0.020)、低色素血症(p=0.001)、多色素血症(p=0.013)、rouleaux形成(p=0.004)和非典型淋巴细胞(p=0.011)和疟疾寄生虫血症(p=0.001)的百分比显著较高。红细胞异数增多和低色素血症是贫血的基本特征,已被证明与饮酒有关。这意味着过量饮酒可能对血液学变量产生不利影响,特别是会增加患贫血的风险。
Investigating the Impact of Alcohol Consumption on Some Haematological Variables among Alcohol Consumers in Jos Metropolis, Nigeria
Ethanol is contained in alcoholic beverages, which are produced by the process of fermentation of grains, fruits, and other sources of sugar. The effect of alcohol consumption among youths and adults resulting to escalating crime rate in the society has generated great concern. The impact of alcohol consumption on haematological variables has not been well documented in Jos metropolis. The study sought to establish whether alcohol consumption has any effect on the haematological status of individuals or not. Following informed consent, we determined haematocrit values by the microhaematocrit method, haemoglobin (Hb) concentration by cyanmethaemoglobin technique, total and differential white blood cell counts (WBC), malaria parasite as well as microscopic blood film reporting of 124 alcohol consumers and 53 non-consumers as a control. SPSS version 23 was used to compare mean values between alcohol consumers and the control group (student t-test), while associations of blood film report were determined by chi-square. Results showed a significantly higher total lymphocytes count among alcohol consumers compared to nonalcohol consumers (48.28±12.98 v 41.91±11.59; p=0.002). Also, the blood film reporting revealed a significantly higher percentages of macrocytes (p=0.001), microcytes (p=0.020), hypochromia (p=0.001), polychromasia (p=0.013), rouleaux formation (p=0.004) and atypical lymphocytes (p=0.011) and malaria parasitaemia (p=0.001) among alcohol consumers compared to the control group. Anisocytosis and hypochromia, which are essential characteristic features of anaemia, have been shown to associate with alcohol consumption. The implication is that excessive alcohol intake may impact adversely on haematological variables, and particularly constitute an increased risk of developing anaemia.