乙型地中海贫血患者血清中与尿酸相关的弓形虫病的患病率

Wurood Alwan Kadhim, Ahmed Khudhair Al-Hamairy
{"title":"乙型地中海贫血患者血清中与尿酸相关的弓形虫病的患病率","authors":"Wurood Alwan Kadhim, Ahmed Khudhair Al-Hamairy","doi":"10.21931/rb/css/s2023.08.01.43","DOIUrl":null,"url":null,"abstract":"Laboratory experiments were performed to study 66 samples were collected for\nbeta-thalassemia patients, with 30 samples for control of healthy people, male\nand female, and 96 samples were examined in the Cobas e411 Advice for both\nIgG and IgM, 20 samples were obtained positive for IgG in patients with betathalassemia, and one sample was positive for IgM, then the Uric Acid examination was conducted for all After that, 12 male and female samples were selected\nwith a high percentage of Uric Acid, 6 of which were positive for Toxoplasmosis\nand 6 negatives for the disease. To perform the Performance Liquid Chromatography (HPLC) technique and use the standard substance allantoin to observe the\nrelationship between Uric Acid and Allantoin, where the relationship is inverse\nbetween them; in the case of infection and the presence of the parasite in the\nblood, the Uric Acid oxidizes and combines with the free radicals (reactive oxygen species) in the blood such as oxygen and hydrogen peroxide that are harmful\nto the cell or tissue. Free radicals in abundance and as a guide to the extent of\ndamage performed by the parasite.\nKeywords: beta-thalassemia, Uric Acid, Allantoin, Toxoplasmosis, IgG and\nIgM.","PeriodicalId":443152,"journal":{"name":"Sumer 1","volume":"17 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Seroprevalence of toxoplasmosis related with uric acid in B-thalassemia\\nmajor patients\",\"authors\":\"Wurood Alwan Kadhim, Ahmed Khudhair Al-Hamairy\",\"doi\":\"10.21931/rb/css/s2023.08.01.43\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Laboratory experiments were performed to study 66 samples were collected for\\nbeta-thalassemia patients, with 30 samples for control of healthy people, male\\nand female, and 96 samples were examined in the Cobas e411 Advice for both\\nIgG and IgM, 20 samples were obtained positive for IgG in patients with betathalassemia, and one sample was positive for IgM, then the Uric Acid examination was conducted for all After that, 12 male and female samples were selected\\nwith a high percentage of Uric Acid, 6 of which were positive for Toxoplasmosis\\nand 6 negatives for the disease. To perform the Performance Liquid Chromatography (HPLC) technique and use the standard substance allantoin to observe the\\nrelationship between Uric Acid and Allantoin, where the relationship is inverse\\nbetween them; in the case of infection and the presence of the parasite in the\\nblood, the Uric Acid oxidizes and combines with the free radicals (reactive oxygen species) in the blood such as oxygen and hydrogen peroxide that are harmful\\nto the cell or tissue. Free radicals in abundance and as a guide to the extent of\\ndamage performed by the parasite.\\nKeywords: beta-thalassemia, Uric Acid, Allantoin, Toxoplasmosis, IgG and\\nIgM.\",\"PeriodicalId\":443152,\"journal\":{\"name\":\"Sumer 1\",\"volume\":\"17 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sumer 1\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21931/rb/css/s2023.08.01.43\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sumer 1","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21931/rb/css/s2023.08.01.43","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

实验室实验研究66个样本进行收集forbeta-thalassemia患者,30样品对于控制健康的人来说,无论女性,和96个样本进行Cobas e411建议bothIgG IgM, 20个样本获得阳性患者免疫球蛋白betathalassemia,和一个样本为IgM阳性,那么尿酸检查所有之后,进行了12个男性和女性样本selectedwith高尿酸的百分比,其中6人弓形虫阳性,6人弓形虫病阴性。采用高效液相色谱(HPLC)技术,用标准品尿囊素观察尿酸与尿囊素的关系,两者呈反比关系;在感染和血液中存在寄生虫的情况下,尿酸会氧化并与血液中的自由基(活性氧)结合,如氧和过氧化氢,这些自由基对细胞或组织有害。自由基丰富,并作为寄生虫造成损害程度的指南。关键词:地中海贫血,尿酸,尿囊素,弓形虫病,IgG和igm
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Seroprevalence of toxoplasmosis related with uric acid in B-thalassemia major patients
Laboratory experiments were performed to study 66 samples were collected for beta-thalassemia patients, with 30 samples for control of healthy people, male and female, and 96 samples were examined in the Cobas e411 Advice for both IgG and IgM, 20 samples were obtained positive for IgG in patients with betathalassemia, and one sample was positive for IgM, then the Uric Acid examination was conducted for all After that, 12 male and female samples were selected with a high percentage of Uric Acid, 6 of which were positive for Toxoplasmosis and 6 negatives for the disease. To perform the Performance Liquid Chromatography (HPLC) technique and use the standard substance allantoin to observe the relationship between Uric Acid and Allantoin, where the relationship is inverse between them; in the case of infection and the presence of the parasite in the blood, the Uric Acid oxidizes and combines with the free radicals (reactive oxygen species) in the blood such as oxygen and hydrogen peroxide that are harmful to the cell or tissue. Free radicals in abundance and as a guide to the extent of damage performed by the parasite. Keywords: beta-thalassemia, Uric Acid, Allantoin, Toxoplasmosis, IgG and IgM.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信