{"title":"乙型地中海贫血患者血清中与尿酸相关的弓形虫病的患病率","authors":"Wurood Alwan Kadhim, Ahmed Khudhair Al-Hamairy","doi":"10.21931/rb/css/s2023.08.01.43","DOIUrl":null,"url":null,"abstract":"Laboratory experiments were performed to study 66 samples were collected for\nbeta-thalassemia patients, with 30 samples for control of healthy people, male\nand female, and 96 samples were examined in the Cobas e411 Advice for both\nIgG and IgM, 20 samples were obtained positive for IgG in patients with betathalassemia, and one sample was positive for IgM, then the Uric Acid examination was conducted for all After that, 12 male and female samples were selected\nwith a high percentage of Uric Acid, 6 of which were positive for Toxoplasmosis\nand 6 negatives for the disease. To perform the Performance Liquid Chromatography (HPLC) technique and use the standard substance allantoin to observe the\nrelationship between Uric Acid and Allantoin, where the relationship is inverse\nbetween them; in the case of infection and the presence of the parasite in the\nblood, the Uric Acid oxidizes and combines with the free radicals (reactive oxygen species) in the blood such as oxygen and hydrogen peroxide that are harmful\nto the cell or tissue. Free radicals in abundance and as a guide to the extent of\ndamage performed by the parasite.\nKeywords: beta-thalassemia, Uric Acid, Allantoin, Toxoplasmosis, IgG and\nIgM.","PeriodicalId":443152,"journal":{"name":"Sumer 1","volume":"17 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Seroprevalence of toxoplasmosis related with uric acid in B-thalassemia\\nmajor patients\",\"authors\":\"Wurood Alwan Kadhim, Ahmed Khudhair Al-Hamairy\",\"doi\":\"10.21931/rb/css/s2023.08.01.43\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Laboratory experiments were performed to study 66 samples were collected for\\nbeta-thalassemia patients, with 30 samples for control of healthy people, male\\nand female, and 96 samples were examined in the Cobas e411 Advice for both\\nIgG and IgM, 20 samples were obtained positive for IgG in patients with betathalassemia, and one sample was positive for IgM, then the Uric Acid examination was conducted for all After that, 12 male and female samples were selected\\nwith a high percentage of Uric Acid, 6 of which were positive for Toxoplasmosis\\nand 6 negatives for the disease. To perform the Performance Liquid Chromatography (HPLC) technique and use the standard substance allantoin to observe the\\nrelationship between Uric Acid and Allantoin, where the relationship is inverse\\nbetween them; in the case of infection and the presence of the parasite in the\\nblood, the Uric Acid oxidizes and combines with the free radicals (reactive oxygen species) in the blood such as oxygen and hydrogen peroxide that are harmful\\nto the cell or tissue. Free radicals in abundance and as a guide to the extent of\\ndamage performed by the parasite.\\nKeywords: beta-thalassemia, Uric Acid, Allantoin, Toxoplasmosis, IgG and\\nIgM.\",\"PeriodicalId\":443152,\"journal\":{\"name\":\"Sumer 1\",\"volume\":\"17 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sumer 1\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21931/rb/css/s2023.08.01.43\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sumer 1","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21931/rb/css/s2023.08.01.43","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Seroprevalence of toxoplasmosis related with uric acid in B-thalassemia
major patients
Laboratory experiments were performed to study 66 samples were collected for
beta-thalassemia patients, with 30 samples for control of healthy people, male
and female, and 96 samples were examined in the Cobas e411 Advice for both
IgG and IgM, 20 samples were obtained positive for IgG in patients with betathalassemia, and one sample was positive for IgM, then the Uric Acid examination was conducted for all After that, 12 male and female samples were selected
with a high percentage of Uric Acid, 6 of which were positive for Toxoplasmosis
and 6 negatives for the disease. To perform the Performance Liquid Chromatography (HPLC) technique and use the standard substance allantoin to observe the
relationship between Uric Acid and Allantoin, where the relationship is inverse
between them; in the case of infection and the presence of the parasite in the
blood, the Uric Acid oxidizes and combines with the free radicals (reactive oxygen species) in the blood such as oxygen and hydrogen peroxide that are harmful
to the cell or tissue. Free radicals in abundance and as a guide to the extent of
damage performed by the parasite.
Keywords: beta-thalassemia, Uric Acid, Allantoin, Toxoplasmosis, IgG and
IgM.