166601例病态肥胖手术患者的医疗并发症与BMI无关,直接随年龄增长而变化

L. perry
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引用次数: 0

摘要

目的:了解肥胖患者肥胖合并症的年龄分布。方法:对来自Surgical Review Corporation的BOLD数据库的166601例患者的术前数据进行年龄分析。数据:人口统计、BMI和33例肥胖合并症的百分比。统计学:连续变量的方差分析;二分类变量的一般线性模型。结果:BMI和酒精/烟草/物质使用百分比、多囊卵巢综合征、心理健康诊断和假性脑肿瘤随年龄呈负相关。疝、腹膜炎、心绞痛、胆石症、CHF、DVT/PE、纤维肌痛、功能受损、胃食管反流、糖尿病、痛风、高血压、缺血性心脏病、血脂异常、腿部水肿、背痛、肌肉骨骼疼痛、肥胖、低通气、周围血管疾病、肺动脉高压、应激性尿失禁和失业(n=23)的百分比随着年龄的增长而直接增加,在60-70岁和>70岁的人群中达到峰值。哮喘、抑郁症、心理障碍和肝脏疾病在40-60岁之间的发病率最高。结论:在肥胖患者中,体重相关的医疗状况随着年龄的变化而变化很大。年轻患者的身体质量指数最高,酒精/烟草/药物滥用和心理问题最严重。随着年龄的增长,体重相关的心肺、腹部/肝胆、内分泌/代谢和躯体问题逐渐增加。这种按年龄划分的肥胖风险的先进知识可能会提高临床怀疑指数,可能有助于对肥胖患者的推定管理和改善结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Medical complications in 166,601 surgical patients with morbid obesity vary directly with increasing age independent of BMI
Objective: To identify the incidence of obesity co-morbidities by age in patients with obesity. Methods: Pre-operative data on 166,601 patients from the Surgical Review Corporation’s BOLD database was analyzed by age. Data: demographics, BMI, and percent of 33 obesity co-morbidities. Statistics: ANOVA for continuous variables; Dichotomous variables by general linear models. Results: BMI and percent alcohol/tobacco/substance use, PCOS, mental health diagnosis, and pseudotumor cerebri varied inversely by age. Percent hernia, abdominal panniculitis, angina, cholelithiasis, CHF, DVT/PE, fibromyalgia, impaired function, GERD, diabetes, gout, hypertension, ischemic heart disease, dyslipidemia, leg edema, back pain, musculoskeletal pain, obesity hypoventilation, peripheral vascular disease, pulmonary hypertension, stress incontinence, and unemployment (n=23) increased directly with increasing age, peaking in the 60-70 and >70 years cohorts. Asthma, depression, psychologic impairment, and liver disease were highest in the 40-60 decades Conclusions: In patients with obesity, weight-related medical conditions vary dramatically by age. Younger patients had highest BMI and suffered most from alcohol/tobacco/substance abuse and psychological problems. The major weight-related cardiopulmonary, abdominal/hepatobiliary, endocrine/metabolic, and somatic issues increased progressively with each higher decade of age. This advance knowledge of obesity risks by age may raise clinical index of suspicion, possibly facilitating presumptive management of patients with obesity and improved outcomes.
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