评估冠状动脉成形术伴或不伴术后扩张的长期疗效

A. Separham, Amirshahram Beygzadeh, N. Aslanabadi, Ali Heidari Sarvestani
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引用次数: 0

摘要

扩张后与支架同时扩张相关,从而提高血管成形术的效果。然而,急性心肌梗死(AMI)患者的死亡率和发病率增加的风险已被报道,这引起了对其有效性的相当大的争议。材料和方法:在两年的时间里,由于急性冠状动脉综合征(ACS)的临床特征,包括不稳定型心绞痛、非st段抬高型心肌梗死和AMI,所有患者都接受了血管成形术,伴或不伴后扩张手术。患者在血管成形术后进行了12个月的随访,有或没有后扩张。主要终点为介入治疗后冠状动脉TIMI血流。然而,死亡率、ACS再入院、需要量和AMI发生率在12个月内是次要终点。结果:术后扩张组和未术后扩张组在人口学数据方面无显著差异。在随访期间,比较死亡率、AMI患病率、血运重建术干预和主要心脏不良事件发生率(MACE),各组间无显著差异。结论:基于本研究的结果,球囊扩张后与MACE发生率的降低无关。然而,扩张后可能改善这些患者的TIMI流量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluating long-term outcomes of coronary angioplasty with or without post-dilatation
Introduction: Post-dilatation is associated with a simultaneous expansion of the stents that enhances the angioplasty outcomes. However, increased risk of mortality and morbidity has been reported in patients with acute myocardial infarction (AMI) which has provoked considerable controversies concerning its efficiency. Materials and Methods: During a two-year period, all patients underwent angioplasty with or without post-dilatation procedure, due to clinical features of the acute coronary syndrome (ACS), including unstable angina, non-ST-elevated myocardial infarction, and AMI, were included. The patients underwent 12 months of follow-ups after the angioplasty with or without post-dilatation. The primary endpoint was the TIMI flow of coronary artery after intervention. However, mortality, readmission due to ACS, need for revascularization, and incidence of AMI during 12 months, were secondary endpoints. Results: No significant difference was observed in terms of demographic data between the groups with and without post-dilatation. Comparing mortality rate, the prevalence of AMI, intervention for revascularization and incidence of major adverse cardiac events (MACE) during the follow-up period showed no significant difference between the study groups. Conclusion: Based on the findings of the present study, balloon post-dilation was not associated with a reduction in MACE incidence. However, post-dilation may improve the TIMI flow in these patients.
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