室上性心动过速

S. Fitzpatrick, D. Kerr, B. Fitzpatrick, S. Giannakidou, P-R J Domeyer, N. Fragakis, AP. Antoniadis, M. Sotiriadou, V. Vassilikos
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Due to the life-long therapeutic intervention associated with pacemaker implant, there is increasing emphasis on improving QOL in these patients. This study is the first study to investigate the level of pacemaker dependency in patients with dual-chamber devices, its relationship to QOL and cardiac symptoms. Purpose: To determine the relationship between QOL, cardiac symptoms and the level of physiological dependency patients have on their dual chamber pacemaker to maintain AV synchrony. Methods: Thirty three patients with SSS or AV block were enrolled in a single centre, cross sectional study. To ensure patients had a dual chamber pacemaker implanted, participants were purposively recruited. Patients completed both the SF-36 QOL ques- tionnaire and the pacemaker specific Aquarel questionnaire to assess symptoms. The cumulative percentage of atrial and ventricular pacing required to maintain AV synchrony was recorded at clinic when the patient attended for their clinical review. Pacemaker dependency scores were correlated with SF-36 and Aquarel scores to determine if any relationship existed between pacemaker dependency and QOL and symptom scores. Results: Significant improvement in two SF-36 domains were reported by those patients who had increased pacemaker dependency; Vitality (r ¼ 0.41, p < 0.05) and social functioning (r ¼ 0.37, p ¼ < 0.05). Pacemaker dependency was also significantly correlated with the cognition domain of Aquarel (r ¼ -0.51, p ¼ < 0.05). Conclusion: No previous studies have examined relationships that exist between pacemaker dependency, QOL and symptoms in patients with dual chamber devices only. These findings will help supplement current clinical practice and patient educa- tion on QOL and symptom expectations following pacemaker implant. Conclusions: In our a routine is feasible, safe and effective in all procedures, thanks to An EA-EB Objective: The purpose of this study was to evaluate the impact on the quality of life (QoL), of interventional or medical treatment in patients with a history of supraventricular tachycardias (SVTs). Methods: 140 patients with SVTs were enrolled and divided into two groups accord- ing to the therapeutical approach of their personal choice. Group A consisted of 100 patients, (57% females, mean age 46.55 6 11.4 years) who underwent ablation proce- dure and group B consisted of 40 patients (52.5% females, mean age 43.55 6 11.18 years), who were treated medically. HRQoL was assessed using the Short Form-36 Health Survey (SF-36) and the arrhythmia-specific Umea22, translated into the Greek language, at baseline and 3 months after therapy. Results: The total SF-36 score in the ablation group showed a statistically significant increase by 13.75 6 9.7 (22.34%, p < 0.0001), while a statistically significant decrease of 3.85 6 12.163 (7.07%, p ¼ 0.001) was found in the group with pharmaceutical intervention. In the U22 questionnaire, the welfare score for group A increased statistically significant by 4.65 6 3.239 (132.47%, p < 0.0001), while in group B, a smaller increase was shown 0.21 6 2.25 (18.73%, p ¼ 0.003). Subsequently, the score for the inci- dence of episodes showed a statistically significant decrease of 3.31 6 2.312 (66.87%, p < 0.0001) in group A, while for group B episode’s recurrence remained unchanged (reduction by 0.25 6 1.88 (5.34%, p ¼ 0.405). Finally, the severity of episodes showed a statistically significant decrease by 2.21 6 1.641 (38.34%, p < 0.0001) in favour of the ablation, whist in the medically treated group, there was a statistically insignificant reduction of 0.15 6 1.51 (2.65%, p ¼ 0.541). In group A, female sex appears to corre- late with \"Physical Functionality\" (p ¼ 0.023) in the SF-36, while age was correlated with the \"incidence of episodes\" in U22 (p < 0.0001). In the medically treated group, factor \"age\" was statistically significant with both total score of the SF-36 (p ¼ 0.010) and \"symptoms of episodes\" in the U22 (p ¼ 0.001). Conclusion: QoL is markedly affected in patients with SVTs. RF ablation is a proved curative strategy that improves significantly HRQoL, in contrast to medical therapy, where patients remain symptomatic. Introduction and objectives: Current management of asymptomatic adult patients with the Wolff-Parkinson-white (WPW) syndrome remains controversial. Our objective was to analyze the reasons to perform an electrophysiological study (EPS) and abla- tion in asymptomatic patients with WPW and compare the results with the symptomatic patients. Methods: Adult patients with the WPW syndrome submitted for an EPS and ablation were divided between symptomatic (symptoms suggestive of tachycardia incorporat-ing the accessory pathway (AP) or atrial fibrillation) and asymptomatic, considering the reasons to perform the procedure. In all of them we analyzed the electrical and anatomic properties of the AP, the final success and the incidence of complications. Results: We have included 150 patients: 114 asymptomatic (39 6 14 years, 48% male) and 36 asymptomatic (38 6 14 years, 58% male; p ¼ NS). The most frequent symptoms were palpitations (88%) and syncope (5%). In 33% of them the tachycardia was docu-mented and 10% had preexcited atrial fibrillation. Of 154 AP ablated, 56% were left- sided, 17% right-sided and 27% septal, without significant differences between both groups. Anterograde refractory period of the AP was significantly longer in asymptomatic patients (319 6 59 ms) as compared with symptomatic patients (275 6 48 ms; p < 0,001) as well as tachycardia inducibility (67% y 25%; p < 0,001). Successful ablation with one procedure was achieved in 98% of the patients, without major complications. Conclusions: Catheter ablation in adult patients with the WPW syndrome offers excellent results without major complications, and may be performed also in many asymptomatic patients to avoid possible future arrhythmic events.","PeriodicalId":341699,"journal":{"name":"Rapid Cardiac Care","volume":"72 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Supraventricular tachycardia\",\"authors\":\"S. Fitzpatrick, D. Kerr, B. Fitzpatrick, S. Giannakidou, P-R J Domeyer, N. Fragakis, AP. Antoniadis, M. Sotiriadou, V. Vassilikos\",\"doi\":\"10.1002/9781119547808.ch29\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: the management of these patients. AV synchrony has been shown to improve stroke volume and is fundamental in the maintenance of appropriate cardiac output. The physiological pacing provided by dual chamber devices should reduce cardiovascular mortality and morbidity and improve patient quality of life (QOL). It is unclear however if the maintenance of AV synchrony achieved through the artificial means of physiological pacing correlates with intrinsi- cally maintained AV synchrony when comparing QOL scores and cardiac symptoms in these patients. QOL has become recognised as a valuable measure for assessing the benefits that therapeutic interventions such as pacemaker implantation can have on a patients’ well-being. Due to the life-long therapeutic intervention associated with pacemaker implant, there is increasing emphasis on improving QOL in these patients. This study is the first study to investigate the level of pacemaker dependency in patients with dual-chamber devices, its relationship to QOL and cardiac symptoms. Purpose: To determine the relationship between QOL, cardiac symptoms and the level of physiological dependency patients have on their dual chamber pacemaker to maintain AV synchrony. Methods: Thirty three patients with SSS or AV block were enrolled in a single centre, cross sectional study. To ensure patients had a dual chamber pacemaker implanted, participants were purposively recruited. Patients completed both the SF-36 QOL ques- tionnaire and the pacemaker specific Aquarel questionnaire to assess symptoms. The cumulative percentage of atrial and ventricular pacing required to maintain AV synchrony was recorded at clinic when the patient attended for their clinical review. Pacemaker dependency scores were correlated with SF-36 and Aquarel scores to determine if any relationship existed between pacemaker dependency and QOL and symptom scores. Results: Significant improvement in two SF-36 domains were reported by those patients who had increased pacemaker dependency; Vitality (r ¼ 0.41, p < 0.05) and social functioning (r ¼ 0.37, p ¼ < 0.05). Pacemaker dependency was also significantly correlated with the cognition domain of Aquarel (r ¼ -0.51, p ¼ < 0.05). Conclusion: No previous studies have examined relationships that exist between pacemaker dependency, QOL and symptoms in patients with dual chamber devices only. These findings will help supplement current clinical practice and patient educa- tion on QOL and symptom expectations following pacemaker implant. Conclusions: In our a routine is feasible, safe and effective in all procedures, thanks to An EA-EB Objective: The purpose of this study was to evaluate the impact on the quality of life (QoL), of interventional or medical treatment in patients with a history of supraventricular tachycardias (SVTs). Methods: 140 patients with SVTs were enrolled and divided into two groups accord- ing to the therapeutical approach of their personal choice. Group A consisted of 100 patients, (57% females, mean age 46.55 6 11.4 years) who underwent ablation proce- dure and group B consisted of 40 patients (52.5% females, mean age 43.55 6 11.18 years), who were treated medically. HRQoL was assessed using the Short Form-36 Health Survey (SF-36) and the arrhythmia-specific Umea22, translated into the Greek language, at baseline and 3 months after therapy. Results: The total SF-36 score in the ablation group showed a statistically significant increase by 13.75 6 9.7 (22.34%, p < 0.0001), while a statistically significant decrease of 3.85 6 12.163 (7.07%, p ¼ 0.001) was found in the group with pharmaceutical intervention. In the U22 questionnaire, the welfare score for group A increased statistically significant by 4.65 6 3.239 (132.47%, p < 0.0001), while in group B, a smaller increase was shown 0.21 6 2.25 (18.73%, p ¼ 0.003). Subsequently, the score for the inci- dence of episodes showed a statistically significant decrease of 3.31 6 2.312 (66.87%, p < 0.0001) in group A, while for group B episode’s recurrence remained unchanged (reduction by 0.25 6 1.88 (5.34%, p ¼ 0.405). Finally, the severity of episodes showed a statistically significant decrease by 2.21 6 1.641 (38.34%, p < 0.0001) in favour of the ablation, whist in the medically treated group, there was a statistically insignificant reduction of 0.15 6 1.51 (2.65%, p ¼ 0.541). In group A, female sex appears to corre- late with \\\"Physical Functionality\\\" (p ¼ 0.023) in the SF-36, while age was correlated with the \\\"incidence of episodes\\\" in U22 (p < 0.0001). In the medically treated group, factor \\\"age\\\" was statistically significant with both total score of the SF-36 (p ¼ 0.010) and \\\"symptoms of episodes\\\" in the U22 (p ¼ 0.001). Conclusion: QoL is markedly affected in patients with SVTs. RF ablation is a proved curative strategy that improves significantly HRQoL, in contrast to medical therapy, where patients remain symptomatic. Introduction and objectives: Current management of asymptomatic adult patients with the Wolff-Parkinson-white (WPW) syndrome remains controversial. Our objective was to analyze the reasons to perform an electrophysiological study (EPS) and abla- tion in asymptomatic patients with WPW and compare the results with the symptomatic patients. Methods: Adult patients with the WPW syndrome submitted for an EPS and ablation were divided between symptomatic (symptoms suggestive of tachycardia incorporat-ing the accessory pathway (AP) or atrial fibrillation) and asymptomatic, considering the reasons to perform the procedure. In all of them we analyzed the electrical and anatomic properties of the AP, the final success and the incidence of complications. Results: We have included 150 patients: 114 asymptomatic (39 6 14 years, 48% male) and 36 asymptomatic (38 6 14 years, 58% male; p ¼ NS). The most frequent symptoms were palpitations (88%) and syncope (5%). In 33% of them the tachycardia was docu-mented and 10% had preexcited atrial fibrillation. Of 154 AP ablated, 56% were left- sided, 17% right-sided and 27% septal, without significant differences between both groups. Anterograde refractory period of the AP was significantly longer in asymptomatic patients (319 6 59 ms) as compared with symptomatic patients (275 6 48 ms; p < 0,001) as well as tachycardia inducibility (67% y 25%; p < 0,001). Successful ablation with one procedure was achieved in 98% of the patients, without major complications. 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引用次数: 2

摘要

介绍:这些患者的管理。房颤同步已被证明可以改善每搏量,是维持适当心输出量的基础。双室装置提供的生理起搏可降低心血管病死率和发病率,提高患者的生活质量。然而,在比较这些患者的生活质量评分和心脏症状时,尚不清楚通过人工生理起搏手段维持房室同步是否与内在维持房室同步相关。生活质量已被认为是评估诸如心脏起搏器植入等治疗干预措施对患者健康的益处的一种有价值的措施。由于与心脏起搏器植入相关的终身治疗干预,人们越来越重视改善这些患者的生活质量。本研究首次探讨双室起搏器患者的起搏器依赖水平及其与生活质量和心脏症状的关系。目的:探讨双室起搏器维持房室同步的生理依赖程度与患者生活质量、心脏症状的关系。方法:33例SSS或AV阻滞患者入组单中心横断面研究。为了确保患者植入双室起搏器,参与者被有意招募。患者完成SF-36生活质量问卷和起搏器特异性Aquarel问卷来评估症状。当患者参加临床复查时,记录维持房室同步所需的心房和心室起搏的累积百分比。起搏器依赖评分与SF-36和Aquarel评分相关,以确定起搏器依赖与生活质量和症状评分之间是否存在任何关系。结果:起搏器依赖性增加的患者报告了两个SF-36域的显著改善;活力(r = 0.41, p < 0.05)和社会功能(r = 0.37, p < 0.05)。起搏器依赖也与Aquarel认知域显著相关(r¼-0.51,p¼< 0.05)。结论:以往没有研究调查仅双室起搏器患者的起搏器依赖、生活质量和症状之间的关系。这些发现将有助于补充目前的临床实践和患者的生活质量教育和症状预期后植入心脏起搏器。结论:由于EA-EB,我们的常规手术在所有手术中都是可行、安全、有效的。目的:本研究的目的是评估有室上性心动过速(SVTs)病史的患者的介入或药物治疗对生活质量(QoL)的影响。方法:选取140例室性心动过速患者,根据个人选择的治疗方法分为两组。A组100例患者(57%女性,平均年龄46.55 6 11.4岁)行消融术;B组40例患者(52.5%女性,平均年龄43.55 6 11.18岁)行内科治疗。HRQoL在基线和治疗后3个月分别使用SF-36健康调查简表(SF-36)和翻译成希腊语的心律失常特异性Umea22进行评估。结果:消融组SF-36总分上升13.75 6 9.7分(22.34%,p < 0.0001),药物干预组SF-36总分下降3.85 6 12.163分(7.07%,p < 0.001),差异有统计学意义。在U22问卷中,A组福利得分增加了4.65 6 3.239 (132.47%,p < 0.0001),有统计学意义;B组福利得分增加了0.21 6 2.25 (18.73%,p < 0.003),增幅较小。随后,a组的发作发生率评分下降了3.31 6 2.312 (66.87%,p < 0.0001),而B组的发作复发率保持不变(下降了0.25 6 1.88 (5.34%,p < 0.405),具有统计学意义。最后,消融术组患者的发作严重程度降低了2.21 6 1.641 (38.34%,p < 0.0001),而药物治疗组患者的发作严重程度降低了0.15 6 1.51 (2.65%,p < 0.541),但差异无统计学意义。在A组中,女性性别似乎与SF-36中的“身体功能”相关(p < 0.023),而年龄与U22中的“发作发生率”相关(p < 0.0001)。在药物治疗组中,因子“年龄”与SF-36总分(p < 0.010)和U22中的“发作症状”(p < 0.001)均有统计学意义。结论:室性心动过速患者的生活质量受到明显影响。与药物治疗相比,射频消融是一种经证实的治疗策略,可显着改善HRQoL,而药物治疗患者仍有症状。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Supraventricular tachycardia
Introduction: the management of these patients. AV synchrony has been shown to improve stroke volume and is fundamental in the maintenance of appropriate cardiac output. The physiological pacing provided by dual chamber devices should reduce cardiovascular mortality and morbidity and improve patient quality of life (QOL). It is unclear however if the maintenance of AV synchrony achieved through the artificial means of physiological pacing correlates with intrinsi- cally maintained AV synchrony when comparing QOL scores and cardiac symptoms in these patients. QOL has become recognised as a valuable measure for assessing the benefits that therapeutic interventions such as pacemaker implantation can have on a patients’ well-being. Due to the life-long therapeutic intervention associated with pacemaker implant, there is increasing emphasis on improving QOL in these patients. This study is the first study to investigate the level of pacemaker dependency in patients with dual-chamber devices, its relationship to QOL and cardiac symptoms. Purpose: To determine the relationship between QOL, cardiac symptoms and the level of physiological dependency patients have on their dual chamber pacemaker to maintain AV synchrony. Methods: Thirty three patients with SSS or AV block were enrolled in a single centre, cross sectional study. To ensure patients had a dual chamber pacemaker implanted, participants were purposively recruited. Patients completed both the SF-36 QOL ques- tionnaire and the pacemaker specific Aquarel questionnaire to assess symptoms. The cumulative percentage of atrial and ventricular pacing required to maintain AV synchrony was recorded at clinic when the patient attended for their clinical review. Pacemaker dependency scores were correlated with SF-36 and Aquarel scores to determine if any relationship existed between pacemaker dependency and QOL and symptom scores. Results: Significant improvement in two SF-36 domains were reported by those patients who had increased pacemaker dependency; Vitality (r ¼ 0.41, p < 0.05) and social functioning (r ¼ 0.37, p ¼ < 0.05). Pacemaker dependency was also significantly correlated with the cognition domain of Aquarel (r ¼ -0.51, p ¼ < 0.05). Conclusion: No previous studies have examined relationships that exist between pacemaker dependency, QOL and symptoms in patients with dual chamber devices only. These findings will help supplement current clinical practice and patient educa- tion on QOL and symptom expectations following pacemaker implant. Conclusions: In our a routine is feasible, safe and effective in all procedures, thanks to An EA-EB Objective: The purpose of this study was to evaluate the impact on the quality of life (QoL), of interventional or medical treatment in patients with a history of supraventricular tachycardias (SVTs). Methods: 140 patients with SVTs were enrolled and divided into two groups accord- ing to the therapeutical approach of their personal choice. Group A consisted of 100 patients, (57% females, mean age 46.55 6 11.4 years) who underwent ablation proce- dure and group B consisted of 40 patients (52.5% females, mean age 43.55 6 11.18 years), who were treated medically. HRQoL was assessed using the Short Form-36 Health Survey (SF-36) and the arrhythmia-specific Umea22, translated into the Greek language, at baseline and 3 months after therapy. Results: The total SF-36 score in the ablation group showed a statistically significant increase by 13.75 6 9.7 (22.34%, p < 0.0001), while a statistically significant decrease of 3.85 6 12.163 (7.07%, p ¼ 0.001) was found in the group with pharmaceutical intervention. In the U22 questionnaire, the welfare score for group A increased statistically significant by 4.65 6 3.239 (132.47%, p < 0.0001), while in group B, a smaller increase was shown 0.21 6 2.25 (18.73%, p ¼ 0.003). Subsequently, the score for the inci- dence of episodes showed a statistically significant decrease of 3.31 6 2.312 (66.87%, p < 0.0001) in group A, while for group B episode’s recurrence remained unchanged (reduction by 0.25 6 1.88 (5.34%, p ¼ 0.405). Finally, the severity of episodes showed a statistically significant decrease by 2.21 6 1.641 (38.34%, p < 0.0001) in favour of the ablation, whist in the medically treated group, there was a statistically insignificant reduction of 0.15 6 1.51 (2.65%, p ¼ 0.541). In group A, female sex appears to corre- late with "Physical Functionality" (p ¼ 0.023) in the SF-36, while age was correlated with the "incidence of episodes" in U22 (p < 0.0001). In the medically treated group, factor "age" was statistically significant with both total score of the SF-36 (p ¼ 0.010) and "symptoms of episodes" in the U22 (p ¼ 0.001). Conclusion: QoL is markedly affected in patients with SVTs. RF ablation is a proved curative strategy that improves significantly HRQoL, in contrast to medical therapy, where patients remain symptomatic. Introduction and objectives: Current management of asymptomatic adult patients with the Wolff-Parkinson-white (WPW) syndrome remains controversial. Our objective was to analyze the reasons to perform an electrophysiological study (EPS) and abla- tion in asymptomatic patients with WPW and compare the results with the symptomatic patients. Methods: Adult patients with the WPW syndrome submitted for an EPS and ablation were divided between symptomatic (symptoms suggestive of tachycardia incorporat-ing the accessory pathway (AP) or atrial fibrillation) and asymptomatic, considering the reasons to perform the procedure. In all of them we analyzed the electrical and anatomic properties of the AP, the final success and the incidence of complications. Results: We have included 150 patients: 114 asymptomatic (39 6 14 years, 48% male) and 36 asymptomatic (38 6 14 years, 58% male; p ¼ NS). The most frequent symptoms were palpitations (88%) and syncope (5%). In 33% of them the tachycardia was docu-mented and 10% had preexcited atrial fibrillation. Of 154 AP ablated, 56% were left- sided, 17% right-sided and 27% septal, without significant differences between both groups. Anterograde refractory period of the AP was significantly longer in asymptomatic patients (319 6 59 ms) as compared with symptomatic patients (275 6 48 ms; p < 0,001) as well as tachycardia inducibility (67% y 25%; p < 0,001). Successful ablation with one procedure was achieved in 98% of the patients, without major complications. Conclusions: Catheter ablation in adult patients with the WPW syndrome offers excellent results without major complications, and may be performed also in many asymptomatic patients to avoid possible future arrhythmic events.
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