1例高输出量回肠造口术后营养不良癌症患者的营养管理

Adelina Haryono, D. Sunardi, W. Sinaga
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摘要

高输出量造口是回肠造口形成后的并发症,发生率为23%。对于回肠造口产量的极限是否应该定义为高产量,目前还没有普遍的共识。但是,输出量超过2000ml /天,会引起体液和电解质失衡,还会因营养吸收减少而营养不良。特别是对营养不良高危的癌症患者,如果不及时识别和治疗,会进一步恶化患者的营养状况。一例43岁营养不良的女性升结肠癌患者接受肿瘤切除和回肠结肠造口手术。从术后第3天开始,回肠造口流出量急剧增加至2700 mL/d,引起严重的低钠血症、低钾血症和低镁血症。确定的高输出口的危险因素是常规的促动力药物使用和未解决的恶性肿瘤相关腹膜后脓肿。此外,术后第一天食物摄入量的增加,特别是不溶性纤维含量高的食物,是促成因素之一。然后通过脓肿引流、停用促动力剂和给予抗动力剂来解决高输出口。低钠血症和低镁血症在矫正后得到改善,而低钾血症需要更长的时间来解决。维持并逐渐增加肠内营养以防止进一步营养不良。口服低渗液体摄入量限制在1000毫升/天,建议使用等渗溶液。回肠造口术后高分泌期造口量高是预料中的,但彻底的治疗可以防止病人因体液、电解质和营养失衡而恶化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nutritional management of a malnourished cancer patient with high output ileostomy
High output stoma is a complication that may follow ileostomy formation, with an incidence of 23%. There is no general consensus on the limit of ileostomy production to be defined as high output. However, output of more than 2000 mL/day, can cause fluid and electrolyte imbalance, also malnutrition due to reduced nutrient absorption. Delay in recognition and treatment, especially in cancer patient with high risk of malnutrition, can further deteriorate patient’s nutritional status. A 43-year-old malnourished female with ascending colon cancer underwent tumor resection and ileocolostomy surgery. Starting from the third postoperative day, ileostomy effluent drastically increased to 2700 mL/day, causing severe hyponatremia, hypokalemia, and hypomagnesemia. Risk factors of high output stoma identified were routine prokinetic medication use and unresolved malignancy-related retroperitoneal abscess. Moreover, increment of food intake in the first days after surgery, specifically food high in insoluble fiber, was one of the contributing factors. High output stoma was then resolved by abscess drainage, discontinuation of prokinetic agent, and administration of antimotility agent. Hyponatremia and hypomagnesemia improved with correction, whereas hypokalemia needed longer time to resolve. Enteral nutrition was maintained and increased gradually to prevent further malnutrition. Oral hypotonic fluid intake was limited to 1000 mL/day and isotonic solution consumption was advised. High stoma production due to hypersecretory phase after ileostomy was expected, but thorough management would prevent patient’s deterioration that was caused by the fluid, electrolyte, and nutritional imbalances.
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