{"title":"靶向癌症治疗的碳纳米管","authors":"R. Zeineldin","doi":"10.1002/9783527610419.NTLS0241","DOIUrl":null,"url":null,"abstract":"The sections in this article are \n \n \nIntroduction \nCancer \nConventional Cancer Chemotherapy versus Nanocarrier-Mediated Drug Delivery \nChallenges with Chemical Compounds as Therapeutic Agents \nAdvantages of Nanocarriers as Drug-Delivery Vehicles \n \n \nCarbon Nanotubes as Drug-Delivery Vehicles \nCellular Uptake of CNTs \nFunctionalization of CNTs with Polyethylene Glycol \nTargeting of Cancers \nPassive Targeting \nActive Targeting \nTrafficking of Targeted Drug-Delivery Vehicles \n \n \nTargeted Cancer Therapy Employing CNTs and a Critique of Current Studies \nerbB Family Members \nFolate Receptor α \nBiotin Receptor \nIntegrins \nMarkers for Lymphomas or Leukemias \nDisialoganglioside (GD2) \n \n \nSummary and Future Perspective \nAcknowledgments \n \n \nKeywords: \n \nCarbon nanotubes; \nsingle-walled carbon nanotubes; \nmulti-walled carbon nanotubes; \ncancer; \ntargeting; \nPEGylation; \ndrug delivery","PeriodicalId":312946,"journal":{"name":"Nanotechnologies for the Life Sciences","volume":"20 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2012-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Carbon Nanotubes for Targeted Cancer Therapy\",\"authors\":\"R. Zeineldin\",\"doi\":\"10.1002/9783527610419.NTLS0241\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The sections in this article are \\n \\n \\nIntroduction \\nCancer \\nConventional Cancer Chemotherapy versus Nanocarrier-Mediated Drug Delivery \\nChallenges with Chemical Compounds as Therapeutic Agents \\nAdvantages of Nanocarriers as Drug-Delivery Vehicles \\n \\n \\nCarbon Nanotubes as Drug-Delivery Vehicles \\nCellular Uptake of CNTs \\nFunctionalization of CNTs with Polyethylene Glycol \\nTargeting of Cancers \\nPassive Targeting \\nActive Targeting \\nTrafficking of Targeted Drug-Delivery Vehicles \\n \\n \\nTargeted Cancer Therapy Employing CNTs and a Critique of Current Studies \\nerbB Family Members \\nFolate Receptor α \\nBiotin Receptor \\nIntegrins \\nMarkers for Lymphomas or Leukemias \\nDisialoganglioside (GD2) \\n \\n \\nSummary and Future Perspective \\nAcknowledgments \\n \\n \\nKeywords: \\n \\nCarbon nanotubes; \\nsingle-walled carbon nanotubes; \\nmulti-walled carbon nanotubes; \\ncancer; \\ntargeting; \\nPEGylation; \\ndrug delivery\",\"PeriodicalId\":312946,\"journal\":{\"name\":\"Nanotechnologies for the Life Sciences\",\"volume\":\"20 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-02-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nanotechnologies for the Life Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/9783527610419.NTLS0241\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanotechnologies for the Life Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/9783527610419.NTLS0241","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The sections in this article are
Introduction
Cancer
Conventional Cancer Chemotherapy versus Nanocarrier-Mediated Drug Delivery
Challenges with Chemical Compounds as Therapeutic Agents
Advantages of Nanocarriers as Drug-Delivery Vehicles
Carbon Nanotubes as Drug-Delivery Vehicles
Cellular Uptake of CNTs
Functionalization of CNTs with Polyethylene Glycol
Targeting of Cancers
Passive Targeting
Active Targeting
Trafficking of Targeted Drug-Delivery Vehicles
Targeted Cancer Therapy Employing CNTs and a Critique of Current Studies
erbB Family Members
Folate Receptor α
Biotin Receptor
Integrins
Markers for Lymphomas or Leukemias
Disialoganglioside (GD2)
Summary and Future Perspective
Acknowledgments
Keywords:
Carbon nanotubes;
single-walled carbon nanotubes;
multi-walled carbon nanotubes;
cancer;
targeting;
PEGylation;
drug delivery